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Loss of Dystroglycan Drives Cellular Senescence via Defective Mitosis-Mediated Genomic Instability

• Authors : Jimenez-Gutierrez, Guadalupe Elizabeth; Mondragon-Gonzalez, Ricardo; Soto-Ponce, Luz Adriana

Subjects: β-Dystroglycan; cellular senescence; lamin B1

• Source: Jimenez-Gutierrez , G E , Mondragon-Gonzalez , R , Soto-Ponce , L A , Gómez-Monsiváis , W L , García-Aguirre , I , Pacheco-Rivera , R A , Suárez-Sánchez , R , Brancaccio , A , Javier Magaña , J

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Cellular senescence in the aging retina and developments of senotherapies for age-related macular degeneration

• Authors : Lee, Keng Siang; Lin, Shuxiao; Copland, David A

• Source: Lee , K S , Lin , S , Copland , D A , Dick , A D & Liu , J 2021 , ' Cellular senescence in the aging retina and developments of

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Senescence in the ageing skin:a new focus on mTORC1 and the lysosome

• Authors : Smith, Phineas; Carroll, Bernadette

• Source: Smith , P & Carroll , B 2024 , ' Senescence in the ageing skin : a new focus on mTORC1 and the lysosome ' , The FEBS Journal . https://doi.org/10.1111/febs.17281

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Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner

• Authors : Lagnado, Anthony; Carroll, Bernadette; Passos, João F.

Subjects: aging; neutrophils; senescence

• Source: Lagnado , A , Carroll , B , Passos , J F & al. , E 2021 , ' Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner ' , EMBO Journal ,

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Nutrient sensing, growth and senescence

• Authors : Carroll, Bernadette; Korolchuk, Viktor I.

Subjects: ageing; autophagy; growth

• Source: Carroll , B & Korolchuk , V I 2018 , ' Nutrient sensing, growth and senescence ' , FEBS Journal , vol. 285 , no. 11 , pp. 1948-1958 . https://doi.org/10.1111/febs.14400

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Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule

• Authors : Kelly, George; Kataura, Tetsushi; Panek, Johan

• Source: Kelly , G , Kataura , T , Panek , J , Ma , G , Salmonowicz , H , Davis , A , Kendall , H , Brookes , C , Ayine-Tora , D M , Banks , P , Nelson , G , Dobby , L , Pitrez , P R , Booth , L , Costello , L

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Accelerated cardiac aging in patients with congenital heart disease

• Authors : Iacobazzi, Dominga; Alvino, Valeria V; Caputo, Massimo

Subjects: aging; congenital defect; proteostasis

• Source: Iacobazzi , D , Alvino , V V , Caputo , M & Madeddu , P R 2022 , ' Accelerated cardiac aging in patients with congenital heart disease ' , Frontiers in Cardiovascular Medicine , vol. 9 , 892861 .

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shRNA-mediated PPARα knockdown in human glioma stem cells reduces in vitro proliferation and inhibits orthotopic xenograft tumour growth

• Authors : Haynes, H R; Scott, H L; Killick-Cole, C L

Subjects: /dk/atira/pure/core/keywords/brain_and_behaviour; name=Brain and Behaviour; PPARα

• Source: Haynes , H R , Scott , H L , Killick-Cole , C L , Shaw , G , Brend , T , Hares , K M , Redondo , J , Kemp , K C , Ballesteros , L S , Herman , A , Cordero-Llana , O , Singleton , W G , Mills , F ,

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The mTORC1-autophagy pathway is a target for senescent cell elimination

• Authors : Kucheryavenko, Olena; Nelson, Glyn; von Zglinicki, Thomas

• Source: Kucheryavenko , O , Nelson , G , von Zglinicki , T , Korolchuk , V I & Carroll , B 2019 , ' The mTORC1-autophagy pathway is a target for senescent cell elimination ' , Biogerontology , vol. 20 , no. 3

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Rapamycin improves healthspan but not inflammaging in nfκb1 −/− mice

• Authors : Correia-Melo, Clara; Birch, Jodie; Fielder, Edward

Subjects: aging; inflammaging; mTOR

• Source: Correia-Melo , C , Birch , J , Fielder , E , Rahmatika , D , Taylor , J , Chapman , J , Lagnado , A , Carroll , B M , Miwa , S , Richardson , G , Jurk , D , Oakley , F , Mann , J , Mann , D A ,

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