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النتائج لكل صفحة: 10
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Collection : Lilloa (Hal Lille Open Archive, Universite De Lille)
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Dissertation/ Thesis

Nanotubes as a new pathway for the transfer and propagation of pathological Tau protein ; Les nanotubes comme nouvelle voie de transfert et de propagation de la protéine Tau pathologique

Subjects: Video-microscopy; Vesicular transport; Neurons

  • Source: https://theses.hal.science/tel-01864018 ; Médecine humaine et pathologie. Université du Droit et de la Santé - Lille II, 2017. Français. ⟨NNT : 2017LIL2S045⟩.

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Dissertation/ Thesis

Functional characterization and implication in Alzheimer's disease of a new truncated form of the Tau protein ; Caractérisation fonctionnelle et implication dans la maladie d’Alzheimer d’une nouvelle forme tronquée de la protéine Tau

Subjects: Alzheimer's disease; Tau protein; Protéine Tau

  • Source: https://theses.hal.science/tel-03857557 ; Médecine humaine et pathologie. Université du Droit et de la Santé - Lille II, 2017. Français. ⟨NNT : 2017LIL2S060⟩.

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Academic Journal

A selection and optimization strategy for single-domain antibodies targeting the PHF6 linear peptide within the Tau intrinsically disordered protein

Subjects: antibody engineering; nuclear magnetic resonance (NMR); protein aggregation

  • Source: ISSN: 0021-9258.

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Academic Journal

Atypical, non-standard functions of the microtubule associated Tau protein

Subjects: Tau; Alzheimer’s disease; Neuronal function

  • Source: ISSN: 2051-5960 ; Acta Neuropathologica Communications ; https://inserm.hal.science/inserm-01654098 ; Acta Neuropathologica Communications, 2016, 5 (1), pp.91. ⟨10.1186/s40478-017-0489-6⟩.

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Academic Journal

Tunneling nanotube (TNT)-mediated neuron-to neuron transfer of pathological Tau protein assemblies

Subjects: [SDV]Life Sciences [q-bio]

  • Source: EISSN: 2051-5960 ; Acta Neuropathologica Communications ; https://inserm.hal.science/inserm-01391925 ; Acta Neuropathologica Communications, 2016, 4 (1), pp.117. ⟨10.1186/s40478-016-0386-4⟩

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Academic Journal

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: Relevance to sporadic tauopathies.

Subjects: Alzheimer; Prion; Propagation

  • Source: ISSN: 2051-5960 ; Acta Neuropathologica Communications ; https://inserm.hal.science/inserm-00945726 ; Acta Neuropathologica Communications, 2014, 2 (1), pp.14. ⟨10.1186/2051-5960-2-14⟩.

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Dissertation/ Thesis

Uncovering the role of Tau protein in the regulation of glucose homeostasis ; Exploration du rôle de la protéine Tau dans la régulation de l'homéostasie du glucose

Subjects: Pancreas; Tau; Glucose homeostasis

  • Source: https://theses.hal.science/tel-04770732 ; Neurons and Cognition [q-bio.NC]. Université de Lille, 2022. English. ⟨NNT : 2022ULILS036⟩.

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Academic Journal

Shaping the future of preclinical development of successful disease-modifying drugs against Alzheimer's disease: a systematic review of tau propagation models

Subjects: Tau protein; Propagation; Spreading

  • Source: ISSN: 2051-5960 ; Acta Neuropathologica Communications ; https://hal.univ-lille.fr/hal-04684931 ; Acta Neuropathologica Communications, 2024, Acta Neuropathologica Communications, 12 (1), pp.52.

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Dissertation/ Thesis

Atypical functions of Tau protein : roles in nucleic acid protection and RNA metabolism ; Fonctions atypiques de la protéine Tau : rôles dans la protection des acides nucléiques et le métabolisme des ARN

Subjects: Tau protein; RNA damage; DNA damage

  • Source: https://theses.hal.science/tel-02613476 ; Médecine humaine et pathologie. Université du Droit et de la Santé - Lille II, 2016. Français. ⟨NNT : 2016LIL2S054⟩.

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Dissertation/ Thesis

The role of a new truncated form of Tau protein in the development of Alzheimer's disease and its therapeutic potential ; Le rôle d’une nouvelle forme tronquée de la protéine Tau dans le développement de la maladie d’Alzheimer et son potentiel thérapeutique

Subjects: Truncation; Alzheimer's Disease; Tau proteins

  • Source: https://theses.hal.science/tel-04981723 ; Neurosciences. Université de Lille, 2020. Français. ⟨NNT : 2020LILUS021⟩.

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