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النتائج لكل صفحة: 10
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Collection : Hal-Cea (Commissariat A L'energie Atomique Et Aux Energies Alternatives)
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Academic Journal

Tau co-organizes dynamic microtubule and actin networks.

Subjects: Microtubule associated protein; Tau Protein; Cytoskeleton

  • Source: ISSN: 2045-2322.

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Academic Journal

Development of an AAV-based model of tauopathy targeting retinal ganglion cells and the mouse visual pathway to study the role of microglia in Tau pathology

Subjects: [SDV]Life Sciences [q-bio]

  • Source: ISSN: 0969-9961.

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Academic Journal

Long-term clinical and biological prognostic factors of anti-NMDA receptor encephalitis in children

Subjects: [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]

  • Source: ISSN: 2332-7812 ; Neurology Neuroimmunology & Neuroinflammation ; https://hal.science/hal-05028880 ; Neurology Neuroimmunology & Neuroinflammation, 2025, 12 (2), pp.e200346.

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Dissertation/ Thesis

Multiplex quantification of biomarkers and their proteoforms by mass spectrometry for the differential diagnosis of neurodegenerative diseases ; Quantification multiplexe de biomarqueurs et de leurs protéoformes par spectrométrie de masse pour le diagnostic différentiel de maladies neurodégénératives

Subjects: Differential diagnosis; Biomarkers BMs; Mass spectrometry

  • Source: https://theses.hal.science/tel-04913014 ; Chimie analytique. Université Paris-Saclay, 2023. Français. ⟨NNT : 2023UPASF006⟩.

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Dissertation/ Thesis

Development of a new gene-transfer model in mice to study tauopathy spreading : influence of tau aggregation and microglia activation ; Développement d'un nouveau modèle murin par transfert de gène pour étudier la propagation de la tauopathie : influence de l'agrégation de la protéine tau et de l'activation microgliale

Subjects: Trem2; Toxic species of Tau; Microglia

  • Source: https://theses.hal.science/tel-04287541 ; Neurobiologie. Université Paris-Saclay, 2023. Français. ⟨NNT : 2023UPASL092⟩.

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Academic Journal

A seeding-based neuronal model of tau aggregation for use in drug discovery

Subjects: [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology; [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology

  • Source: ISSN: 1932-6203.

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Academic Journal

Novel repertoire of tau biosensors to monitor pathological tau transformation and seeding activity in living cells

Subjects: [SDV]Life Sciences [q-bio]

  • Source: EISSN: 2050-084X ; eLife ; https://hal.science/hal-04300669 ; eLife, 2023, 12, ⟨10.7554/elife.78360⟩

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Academic Journal

A biomimetic multiparametric assay to characterise anti-amyloid drugs

Subjects: Chicago sky blue; indomethacin; bexarotene

  • Source: ISSN: 1661-6596.

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Dissertation/ Thesis

Evaluation of the impact of the mutations associated with Alzheimer's disease in the context of the brain development using induced pluripotent stem cells (iPSCs) and a Brain organoid model ; Évaluation de l'impact des mutations associées à la Maladie d'Alzheimer dans le contexte du développement du cerveau à l'aide de cellules souches pluripotentes (CSIPs) et d'un modèle d'organoïdes cérébraux

Subjects: Alzheimer's disease; Ipsc; Brain organoid

  • Source: https://theses.hal.science/tel-05268688 ; Neurobiologie. Université Paris-Saclay, 2025. Français. ⟨NNT : 2025UPASL035⟩.

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Dissertation/ Thesis

Role of Neuroinflammation and the TREM2 Microglial Receptor in the Progression of two Models of Tauopathy ; Rôle de la neuroinflammation et du récepteur microglial TREM2 dans la progression de deux modèles de tauopathie

Subjects: In vivo models; Neuroinflammation; Tauopathy

  • Source: https://theses.hal.science/tel-03276300 ; Neurosciences [q-bio.NC]. Université Paris Saclay (COmUE), 2019. Français. ⟨NNT : 2019SACLS170⟩.

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