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Academic Journal

Dipeptidyl peptidase-1 inhibition with brensocatib reduces the activity of all major neutrophil serine proteases in patients with bronchiectasis:results from the WILLOW trial

Subjects: Humans; Serine Proteases/pharmacology; Neutrophils

  • Source: Cipolla, D, Zhang, J, Korkmaz, B, Chalmers, J D, Basso, J, Lasala, D, Fernandez, C, Teper, A, Mange, K C, Perkins, W R & Sullivan, E J 2023, 'Dipeptidyl peptidase-1 inhibition with brensocatib reduces

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Academic Journal

Commentary on Urinary L-erythro-β-hydroxyasparagine:a novel serine racemase inhibitor and substrate of the Zn 2+ -dependent D-serine dehydratase

Subjects: d-serine; amino acids; serine racemase

  • Source: Tamaki, F K 2021, 'Commentary on Urinary L-erythro-β-hydroxyasparagine : a novel serine racemase inhibitor and substrate of the Zn 2+ -dependent D-

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Academic Journal

Targeting neutrophil serine proteases in bronchiectasis

Subjects: /dk/atira/pure/subjectarea/asjc/2700/2740; name=Pulmonary and Respiratory Medicine

  • Source: Chalmers, J D, Mall, M A, Chotirmall, S H, O’Donnell, A E, Flume, P A, Hasegawa, N, Ringshausen, F C, Watz, H, Xu, J-F, Shteinberg, M & McShane, P J 2024, 'Targeting neutrophil

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Academic Journal

Neutrophil serine proteases in cystic fibrosis:role in disease pathogenesis and rationale as a therapeutic target

Subjects: /dk/atira/pure/subjectarea/asjc/2700/2740; name=Pulmonary and Respiratory Medicine

  • Source: Mall, M A, Davies, J C, Donaldson, S H, Jain, R, Chalmers, J D & Shteinberg, M 2024, 'Neutrophil serine proteases in cystic fibrosis : role in disease pathogenesis and

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Academic Journal

The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites

Subjects: activity-based probes; chemical proteomics; lipid metabolism

  • Source: Yoo, E, Schulze, C J, Stokes, B H, Onguka, O, Yeo, T, Mok, S, Gnädig, N F, Zhou, Y, Kurita, K, Foe, I T, Terrell, S M, Boucher, M J, Cieplak, P, Kumpornsin, K, Lee, M C S, Linington, R G, Long, J Z,

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Academic Journal

CREB serine 133 is necessary for spatial cognitive flexibility and long-term potentiation

Subjects: CREB; Cyclic AMP response element-binding protein; LTP

  • Source: Morè, L, Privitera, L, Perrett, P, Cooper, D D, Bonnello, M V G, Arthur, J S C & Frenguelli, B G 2022, 'CREB serine 133 is necessary for spatial cognitive flexibility

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Academic Journal

Functions and regulation of the serine/threonine protein kinase CK1 family:moving beyond promiscuity

Subjects: CK1; FAM83; Wnt

  • Source: Fulcher, L J & Sapkota, G P 2020, 'Functions and regulation of the serine/threonine protein kinase CK1 family : moving beyond promiscuity', Biochemical Journal, vol.

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Academic Journal

Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

Subjects: Animals; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism; Protein Kinases/metabolism

  • Source: Bagnoli, E, Lin, Y-E, Burel, S, Jaimon, E, Antico, O, Themistokleous, C, Nikoloff, J M, Squires, S, Morella, I, Watzlawik, J O, Fiesel, F C, Springer, W, Tonelli, F, Lis, P, Brooks, S P, Dunnett, S B,

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