نتائج البحث

The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals

• Authors : Henderson, Colin J; McLaren, Aileen; MacLeod, Andrew K.

Subjects: CAR; CITCO; Constitutive androgen receptor

• Source: Henderson, C J, McLaren, A, MacLeod, A K, Lin, D, Cameron, A, Chatham, L R, Moggs, J G, Inesta-Vaquera, F, Thomson, J P, Meehan, R, Chakravarty, P, Wolf, R & Schwarz, M 2025, 'The potent human CAR

تفاصيل العنوان

Repeated sensitization of mice with microfilariae of Litomosoides sigmodontis induces pulmonary eosinophilia in an IL-33-dependent manner

• Authors : Lenz, Benjamin; Ehrens, Alexandra; Ajendra, Jesuthas

Subjects: Humans; Animals; Mice

• Source: Lenz, B, Ehrens, A, Ajendra, J, Risch, F, Gal, J, Neumann, A-L, Reichwald, J J, Strutz, W, McSorley, H J, Martin, C, Hoerauf, A & Hübner, M P 2024, 'Repeated sensitization of

تفاصيل العنوان

Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas.

• Authors : Fajac, Anne; Simeonova, Iva; Leemput, Julia

Subjects: Animals; Tumor Suppressor Protein p53/genetics; Mice

• Source: Fajac, A, Simeonova, I, Leemput, J, Gabriel, M, Morin, A, Lejour, V, Hamon, A, Rakotopare, J, Vaysse-Zinkhöfer, W, Eldawra, E, Pinskaya, M, Morillon, A, Bourdon, J-C, Bardot, B & Toledo, F 2024,

تفاصيل العنوان

Hydroxysteroid 17β-dehydrogenase 13 (Hsd17b13) knockdown attenuates liver steatosis in high-fat diet obese mice

• Authors : Mahmood, Shehroz; Morrice, Nicola; Thompson, Dawn

• Source: Mahmood, S, Morrice, N, Thompson, D, Milanizadeh, S, Wilson, S, Whitfield, P D, Mcilroy, G, Rochford, J J & Mody, N 2025, 'Hydroxysteroid 17β-dehydrogenase 13 (Hsd17b13) knockdown attenuates liver

تفاصيل العنوان

Improving the predictive power of xenograft and syngeneic anti-tumour studies using mice humanised for pathways of drug metabolism

• Authors : Henderson, Colin J.; McLaren, Aileen W.; Kapelyukh, Yury

Subjects: humanised P450 model; transgenic mice; drug metabolism

• Source: Henderson, C J, McLaren, A W, Kapelyukh, Y & Wolf, C R 2023, 'Improving the predictive power of xenograft and syngeneic anti-tumour studies using mice humanised for

تفاصيل العنوان

Methods to estimate body temperature and energy expenditure dynamics in fed and fasted laboratory mice:effects of sleep deprivation and light exposure

• Authors : van der Vinne, Vincent; McKillop, Laura E.; Wilcox, Sian L.

Subjects: 3R’s; Body compartments; Intraperitoneal

• Source: van der Vinne, V, McKillop, L E, Wilcox, S L, Cantley, J, Peirson, S N, Swoap, S J & Vyazovskiy, V V 2024, 'Methods to estimate body temperature and energy expenditure dynamics in fed and fasted

تفاصيل العنوان

Limiting Extracellular Matrix Expansion in Diet-Induced Obese Mice Reduces Cardiac Insulin Resistance and Prevents Myocardial Remodelling

• Authors : Musale, Vishal; Murdoch, Colin E.; Banah, Ayman K.

Subjects: Cardiac dysfunction; Cardiac insulin resistance; Extracellular matrix remodelling

• Source: Musale, V, Murdoch, C E, Banah, A K, Hasib, A, Hennayake, C K, Dong, B, Lang, C C, Wasserman, D H & Kang, L 2024, 'Limiting Extracellular Matrix Expansion in Diet-Induced Obese

تفاصيل العنوان

Helminth induced monocytosis conveys protection from respiratory syncytial virus infection in mice

• Authors : Burgess, Matthew O.; Janas, Piotr; Berry, Karla

Subjects: helminth; innate immunity; mononuclear phagocyte

• Source: Burgess, M O, Janas, P, Berry, K, Mayr, H, Mack, M, Jenkins, S J, Bain, C C, McSorley, H J & Schwarze, J 2024, 'Helminth induced monocytosis conveys protection from respiratory syncytial virus

تفاصيل العنوان

PolyGR and polyPR knock-in mice reveal a conserved neuroprotective extracellular matrix signature in C9orf72 ALS/FTD neurons

• Authors : Milioto, Carmelo; Carcolé, Mireia; Giblin, Ashling

Subjects: /dk/atira/pure/subjectarea/asjc/2800/2800; name=General Neuroscience

• Source: Milioto, C, Carcolé, M, Giblin, A, Coneys, R, Attrebi, O, Ahmed, M, Harris, S S, Lee, B I, Yang, M, Ellingford, R A, Nirujogi, R S, Biggs, D, Salomonsson, S, Zanovello, M, de Oliveira, P, Katona, E,

تفاصيل العنوان

Head-to-head comparison of BAM15, semaglutide, rosiglitazone, NEN, and calorie restriction on metabolic physiology in female db/db mice

• Authors : Chen, Sing-Young; Beretta, Martina; Olzomer, Ellen M.

Subjects: Mitochondrial uncoupling; Diabetes; Obesity

• Source: Chen, S-Y, Beretta, M, Olzomer, E M, Alexopoulos, S J, Shah, D P, Byrne, F L, Salamoun, J M, Garcia, C J, Smith, G C, Larance, M, Philp, A, Turner, N, Santos, W L, Cantley, J & Hoehn, K L 2024,

تفاصيل العنوان