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  • 1-8 ل  8 نتائج ل ""protein misfolding""
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Academic Journal

Functional and In-silico analysis of ATP8A2 and other P4-ATPase variants associated with human genetic diseases

Subjects: Adenosine Triphosphatases/metabolism; Cerebellar Ataxia/genetics; Computer Simulation

  • Source: Matsell, E, Andersen, J P & Molday, R S 2024, 'Functional and In-silico analysis of ATP8A2 and other P4-ATPase variants associated with human genetic diseases', Disease Models & Mechanisms, vol. 17,

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Academic Journal

The serine protease HtrA1 cleaves misfolded transforming growth factor β-induced protein (TGFBIp) and induces amyloid formation

Subjects: BETA-IG-H3; BIGH3; CORNEA

  • Source: Poulsen, E T, Nielsen, N S, Scavenius, C, Mogensen, E H, Risør, M W, Runager, K, Lukassen, M V, Rasmussen, C B, Christiansen, G, Richner, M, Vorum, H & Enghild, J J 2019, 'The serine protease HtrA1

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Academic Journal

Helicobacter pylori CagA protein is a potent and broad-spectrum amyloid inhibitor

Subjects: Antigens; Bacterial/metabolism; Bacterial Proteins/metabolism

  • Source: Jin, Z, Olsen, W P, Mörman, C, Leppert, A, Kumar, R, Møllebjerg, A, Nielsen, L G, Moshynets, O V, Frasinyuk, M S, Elosua, J Y, Ferreira, D, Abelein, A, Landreh, M, Knight, S D, Johansson, J, Otzen,

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Academic Journal

Specific inhibition of α-synuclein oligomer generation and toxicity by the chaperone domain Bri2 BRICHOS

Subjects: Adaptor Proteins; Signal Transducing/chemistry; Humans

  • Source: Adam, L, Kumar, R, Arroyo-Garcia, L E, Molenkamp, W H, Nowak, J S, Klute, H, Farzadfard, A, Alkenayeh, R, Nielsen, J, Biverstål, H, Otzen, D E, Johansson, J & Abelein, A 2024, 'Specific inhibition of

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Academic Journal

Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

Subjects: Multiple system atrophy (MSA); P25α; Protein aggregation

  • Source: Ferreira, N, Gram, H, Sorrentino, Z A, Gregersen, E, Schmidt, S I, Reimer, L, Betzer, C, Perez-Gozalbo, C, Beltoja, M, Nagaraj, M, Wang, J, Nowak, J S, Dong, M, Willén, K, Cholak, E,

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Academic Journal

Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells

Subjects: ATP11C; ATPase; BINDING

  • Source: Liou, A Y, Molday, L L, Wang, J, Andersen, J P & Molday, R S 2019, 'Identification and functional analyses of disease-associated P4-ATPase phospholipid flippase variants in red blood cells', Journal

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Academic Journal

How internal cavities destabilize a protein

Subjects: high-pressure NMR; protein folding and cooperativity; protein stability

  • Source: Xue, M, Wakamoto, T, Kejlberg, C, Yoshimura, Y, Nielsen, T A, Risør, M W, Sanggaard, K W, Kitahara, R & Mulder, F A A 2019, 'How internal cavities destabilize a

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Academic Journal

Nanostructural Differentiation and Toxicity of Amyloid-β25-35 Aggregates Ensue from Distinct Secondary Conformation

Subjects: ISLET AMYLOID POLYPEPTIDE; ALZHEIMERS-DISEASE; PROTEIN

  • Source: Song, Y, Li, P, Liu, L, Bortolini, C & Dong, M 2018, 'Nanostructural Differentiation and Toxicity of Amyloid-β25-35 Aggregates Ensue from Distinct Secondary Conformation', Scientific Reports, vol. 8,

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  • 1-8 ل  8 نتائج ل ""protein misfolding""