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EZH2 inhibition mitigates HIV immune evasion, reduces reservoir formation, and promotes skewing of CD8 + T cells toward less-exhausted phenotypes

• Authors : Gramatica, Andrea; Miller, Itzayana G.; Ward, Adam R.

Subjects: CP: Immunology; CP: Microbiology; epigenetic regulation

• Source: Gramatica, A, Miller, I G, Ward, A R, Khan, F, Kemmer, T J, Weiler, J, Huynh, T T, Zumbo, P, Kurland, A P,

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Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma

• Authors : Kabatnik, Sonja; Zheng, Xiang; Pappas, Georgios

• Source: Kabatnik, S, Zheng, X, Pappas, G, Steigerwald, S, Padula, M P & Mann, M 2025, 'Deep visual proteomics reveals DNA replication stress as a hallmark of signet ring cell carcinoma', npj Precision

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Soluble immune checkpoints as correlates for HIV persistence and T cell function in people with HIV on antiretroviral therapy

• Authors : Chiu, Chris Y.; Schou, Maya D.; McMahon, James H.

Subjects: HIV; HIV reservoir; HIV-specific T-cell function

• Source: Chiu, C Y, Schou, M D, McMahon, J H, Deeks, S G, Fromentin, R, Chomont, N, Wykes, M N, Rasmussen, T A & Lewin, S R 2023, 'Soluble immune checkpoints as correlates for

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Unequal distribution of genetically-intact HIV-1 proviruses in cells expressing the immune checkpoint markers PD-1 and/or CTLA-4

• Authors : Fisher, Katie; Schlub, Timothy E; Boyer, Zoe

Subjects: Biomarkers/metabolism; CD4-Positive T-Lymphocytes; CTLA-4 Antigen

• Source: Fisher, K, Schlub, T E, Boyer, Z, Rasmussen, T A, Rhodes, A, Hoh, R, Hecht, F M, Deeks, S G, Lewin, S R & Palmer, S 2023, 'Unequal

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Memory CD4 + T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency

• Authors : Rasmussen, Thomas A.; Zerbato, Jennifer M.; Rhodes, Ajantha

Subjects: CTLA4; HIV; HIV cure

• Source: Rasmussen, T A, Zerbato, J M, Rhodes, A, Tumpach, C, Dantanarayana, A, McMahon, J H, Lau, J S Y, Chang, J J, Gubser, C, Brown, W, Hoh, R, Krone, M, Pascoe, R, Chiu, C Y,

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High-dose corticosteroid use and risk of hospitalization for infection in patients treated with immune checkpoint inhibitors - A nationwide register-based cohort study

• Authors : Sørup, Signe; Darvalics, Bianka; Russo, Leo

Subjects: PD-1 immune checkpoint inhibitor; PD-L1 immune checkpoint inhibitor; corticosteroid

• Source: Sørup, S, Darvalics, B, Russo, L, Oksen, D, Lamy, F-X, Verpillat, P, Aa, K, Ht, S & Cronin-Fenton, D 2021, 'High-dose corticosteroid use and risk of hospitalization for infection in patients treated

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A biomimetic yeast shell vaccine coated with layered double hydroxides induces a robust humoral and cellular immune response against tumors

• Authors : Liu, Dong Qun; Lu, Shuai; Zhang, Lun

• Source: Liu , D Q , Lu , S , Zhang , L , Zhang , L X , Ji , M , Liu , X G , Yu , Z & Liu , R T 2020 , ' A biomimetic yeast shell vaccine coated with layered double hydroxides

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Real-world impact of immune checkpoint inhibitors in metastatic uveal melanoma

• Authors : Bol, Kalijn Fredrike; Ellebaek, Eva; Hoejberg, Lise

Subjects: Immune checkpoint inhibitors; Immunotherapy; Real-world data

• Source: Bol, K F, Ellebaek, E, Hoejberg, L, Bagger, M M, Larsen, M S, Klausen, T W, Køhler, U H, Schmidt, H, Bastholt, L, Kiilgaard, J F, Donia, M & Svane, I M 2019,

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Effects of astragalus polysaccharide on immune responses of porcine PBMC stimulated with PRRSV or CSFV

• Authors : Zhuge, Zeng Yu; Zhu, Yao Hong; Liu, Pan Qi

• Source: Zhuge, Z Y, Zhu, Y H, Liu, P Q, Yan, X D, Yue, Y, Weng, X G, Zhang, R & Wang, J F 2012, 'Effects of astragalus polysaccharide on immune responses of porcine PBMC stimulated with PRRSV or CSFV', PLOS

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