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Academic Journal

Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates Macrophage Polarization in Relapsed Melanoma

Subjects: PARP14; T cell exhaustion; quiescent T cells

  • Source: Leshem , R , Sefton , K N , Wong , C W , Lin , I-H , Isaac , D T , Niepel , M & Hurlstone , A 2025 , ' Combined PARP14 Inhibition and PD-1 Blockade Promotes Cytotoxic T Cell Quiescence and Modulates

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Academic Journal

Post-resolution macrophages shape long-term tissue immunity and integrity in a mouse model of pneumococcal pneumonia

Subjects: Animals; Dinoprostone/antagonists & inhibitors; Fibrosis

  • Source: Feehan , K T , Bridgewater , H E , Stenkiewicz-Witeska , J , De maeyer , R P H , Ferguson , J , Mack , M , Brown , J , Ercoli , G , Mawer , C M , Akbar , A N , Glanville , J R W , Jalali , P , Bracken

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Academic Journal

Pro-inflammatory macrophages produce mitochondria-derived superoxide by reverse electron transport at complex I that regulates IL-1β release during NLRP3 inflammasome activation

  • Source: Casey , A M , Ryan , D G , Prag , H A , Chowdhury , S R , Marques , E , Turner , K , Gruszczyk , A V , Yang , M , Wolf , D M , Miljkovic , J L , Valadares , J , Chinnery , P F , Hartley , R C , Frezza

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Academic Journal

Multi-omic analysis of chronic myelomonocytic leukemia monocytes reveals metabolic and immune dysregulation leading to altered macrophage polarization

  • Source: Cant , R , Hull , N J , Wang , Y-H , Somervaille , T C P , Wiseman , D H & Batta , K 2025 , ' Multi-omic analysis of chronic myelomonocytic leukemia monocytes reveals metabolic and immune

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Academic Journal

Amlexanox-loaded nanoliposomes showing enhanced anti-inflammatory activity in cultured macrophages:A potential formulation for treatment of oral aphthous stomatitis

Subjects: Amlexanox; Anti-inflammatory; Aphthous stomatitis

  • Source: Abouzid , A , Moustafa , A Y , Allcock , N , Najlah , M , Elhissi , A , Stanley , C W , Ahmed , W , Seville , P , Crean , S , Forbes , R T & Elsawy , M A 2023 , ' Amlexanox-loaded nanoliposomes

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Academic Journal

Mycobacterium vaccae NCTC 11659, a Soil-Derived Bacterium with Stress Resilience Properties, Modulates the Proinflammatory Effects of LPS in Macrophages

Subjects: IL-10; IL-12; IL-23

  • Source: Holbrook , E M , Zambrano , C A , Wright , C T O , Dubé , E M , Stewart , J R , Sanders , W J , Frank , M G , MacDonald , A S , Reber , S O & Lowry , C A 2023 , ' Mycobacterium vaccae NCTC 11659, a

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Academic Journal

Increased Circulating Chemokines and Macrophage Recruitment in Growing Vestibular Schwannomas

Subjects: Humans; Neuroma; Acoustic/pathology

  • Source: Hannan , C J , Lewis , D , O'Leary , C , Waqar , M , Brough , D , Couper , K N , Dyer , D P , Vail , A , Heal , C , Macarthur , J , Cooper , C , Hammerbeck-Ward , C , Evans , D G , Rutherford , S A ,

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Academic Journal

Macrophage metabolism in the intestine is compartment specific and regulated by the microbiota

Subjects: gut; macrophage; metabolism

  • Source: Scott , N A , Lawson , M A E , Hodgetts , R J , Le Gall , G , Hall , L J & Mann , E R 2022 , ' Macrophage metabolism in the intestine is compartment specific and

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Academic Journal

CD11c identifies microbiota and EGR2-dependent MHCII+ serous cavity macrophages with sexually dimorphic fate in mice

Subjects: macrophage ⋅ peritoneal cavity ⋅ regulation

  • Source: Bain , C C , Louwe , P A , Steers , N J , Bravo-Blas , A , Hegarty , L M , Pridans , C , Milling , S W F , MacDonald , A S , Rückerl , D & Jenkins , S J 2022 , ' CD11c identifies microbiota and

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Academic Journal

Effects of Human RelA Transgene on Murine Macrophage Inflammatory Responses

Subjects: NFκB; RelA(p65); inflammation

  • Source: Papoutsopoulou , S , Morris , L , Bayliff , A , Mair , T , England , H , Stagi , M , Bergey , F , Alam , M T , Tezerji , R S , Rosenstiel , P , Muller , W , santos , V M D & Campbell , B 2022 , '

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