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A meta-analysis of epigenome-wide association studies on pregnancy vitamin B12 concentrations and offspring DNA methylation

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  • معلومة اضافية
    • بيانات النشر:
      eScholarship, University of California, 2023.
    • الموضوع:
      2023
    • نبذة مختصرة :
      Circulating vitamin B12 concentrations during pregnancy are associated with offspring health. Foetal DNA methylation changes could underlie these associations. Within the Pregnancy And Childhood Epigenetics Consortium, we meta-analysed epigenome-wide associations of circulating vitamin B12 concentrations in mothers during pregnancy (n = 2,420) or cord blood (n = 1,029), with cord blood DNA methylation. Maternal and newborn vitamin B12 concentrations were associated with DNA methylation at 109 and 7 CpGs, respectively (False Discovery Rate P-value
    • File Description:
      application/pdf
    • الرقم المعرف:
      10.1080/15592294.2023.2202835
    • الرقم المعرف:
      edssch.oai:escholarship.org:ark:/13030/qt8xv4n01b