Investigating the Relationship Between Serum Ferritin and D-Dimer Levels and Hematological and Biochemical Parameters in Patients With COVID-19

Background and purpose: Ferritin and D-dimer, as biomarkers of inflammation and coagulation disorders, respectively, play an important role in assessing the severity of COVID-19. The aim of this study was to investigate the relationship between these two markers and patients’ demographic, biochemical, hematological, and inflammatory characteristics in COVID-19. Materials and methods: In this retrospective cross-sectional (record-based) study, all patients with confirmed COVID-19 who were hospitalized at Bu Ali Sina Hospital, Sari, between March 2020 and January 2021 were screened. After applying the inclusion and exclusion criteria, a total of 795 patients (442 women and 353 men) were included in the final analysis. Data on ferritin, D-dimer, urea, creatinine, blood glucose, liver enzymes, bilirubin, electrolytes, ESR, CBC, CRP, and coagulation parameters (PT, INR, PTT) were extracted from patient records. Results: Ferritin and D-dimer concentrations were significantly higher in women than in men (P