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Effects of exergaming on exercise capacity in patients with heart failure: results of an international multicentre randomized controlled trial

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  • معلومة اضافية
    • بيانات النشر:
      Linköpings universitet, Avdelningen för omvårdnad och reproduktiv hälsa
      Linköpings universitet, Medicinska fakulteten
      Linköpings universitet, Avdelningen för prevention, rehabilitering och nära vård
      Region Östergötland, Kardiologiska kliniken US
      Rabin Med Ctr, Israel; Tel Aviv Univ, Israel
      Maastricht Univ, Netherlands
      Univ Roma Tor Vergata, Italy
      Univ Bergen, Norway
      Univ Texas Med Branch, TX 77555 USA
      Ctr Clin Res Sudbrandenburg, Germany
      Univ Med Ctr Utrecht, Netherlands; Univ Utrecht, Netherlands
      Karolinska Univ Hosp, Sweden
      AUSL Piacenza, Italy; Univ Parma, Italy
      Jonkoping Univ, Sweden
      WILEY
    • الموضوع:
      2021
    • Collection:
      Linköping University Electronic Press (LiU E-Press)
    • نبذة مختصرة :
      Aims Exergaming is a new tool to increase physical activity. This study aimed to determine the effects of access to a home-based exergame (Nintendo Wii) in patients with heart failure (HF) on exercise capacity, self-reported physical activity and patient-reported outcome measures. Methods and results We enrolled 605 HF patients in New York Heart Association functional class I-IV, independent of ejection fraction, in an international multicentre randomized controlled trial. Patients were randomized to exergame (intervention) or motivational support (control). The primary endpoint was change in submaximal aerobic exercise capacity as measured by the distance walked in 6 min (6MWT) between baseline and 3 months. Secondary endpoints included long-term submaximal aerobic exercise capacity, muscle function, self-reported physical activity, exercise motivation, exercise self-efficacy at 3, 6 and 12months. At baseline, patients on average walked 403142m on the 6MWT. Patients in the exergame group walked further compared to controls at 3 months (454123 vs. 420 +/- 127m, P = 0.005), at 6 months (452 +/- 123 vs. 426 +/- 133m, P = 0.015) and 12months (456 +/- 122 vs. 420 +/- 135m, P = 0.004). However, correcting for baseline 6MWT values by means of a linear mixed-effects model revealed no main effect for the intervention on 6MWT. Small significant effects on muscle function were found. Statistically significant treatment effects were found for muscle function but after correction for baseline and confounders, only the treatment effect for the heel-rise left at 6 months was significant (P<0.05). No treatment effect was found for exercise motivation, exercise self-efficacy, or self-reported physical activity. ConclusionExergaming was safe and feasible in patients with HF with different profiles in different health care systems, cultures and climates. However, it was not effective in improving outcomes on submaximal aerobic exercise capacity. Subgroup analysis did not identify specific subgroups benefiting from the ...
    • File Description:
      application/pdf
    • Relation:
      European Journal of Heart Failure, 1388-9842, 2021, 23:1, s. 114-124; orcid:0000-0002-4197-4026; orcid:0000-0002-7493-0353; orcid:0000-0002-6031-7478; orcid:0000-0002-4259-3671; http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-169342; PMID 32167657; ISI:000563100500001
    • الرقم المعرف:
      10.1002/ejhf.1754
    • الدخول الالكتروني :
      http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-169342
      https://doi.org/10.1002/ejhf.1754
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.F47764C6