نبذة مختصرة : International audience ; The gut microbiome (microbial community with distinct physio-chemical properties in a given habitat 1 ) → major role in maintaining health. • Stratification through the gastrointestinal tract (micro-organisms and metabolites) (Figure 1). • Dysbiosis = unbalanced microbiome → linked to some cancers, inflammatory, metabolic and neurological diseases… • Current methods for the study of the human intestinal microbiome: not representative of the entire gut microbiome. • Faecal analysis: common but do not fully represent the intestinal microbiome (only large bowel). • Endoscopy and colonoscopy: expensive, invasive and complex to implement on a large scale. Could introduce a contamination bias during collection 2 . To overcome these issues, PELICAN HEALTH develops a cutting-edge ingestible device, able to perform multi-sampling in the small intestine (SI) to perform multi-omics analysis (Figure 2).
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