نبذة مختصرة : This study delivers crucial insights into the genomic diversity, AMR, and virulence mechanisms of invasive Salmonella enterica isolates in India. By identifying distinct sequence types, genotypes, and widespread AMR, particularly against quinolones, the research highlights the urgent need for continuous genomic surveillance and evidence-based intervention strategies. The analysis of plasmids and pathogenicity islands illuminates the genetic factors driving the evolution and adaptability of both typhoidal and non-typhoidal Salmonella. These findings will enhance the scientific community’s understanding of Salmonella’s capacity for horizontal gene transfer and environmental adaptation, offering critical insights into the emergence of more virulent and drug-resistant strains.
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