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Bexarotene-Induced Hypertriglyceridemia: A Case Report

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Department of Medicine, Division of Hematology Oncology
    • الموضوع:
      2022
    • Collection:
      University of Massachusetts, Medical School: eScholarship@UMMS
    • نبذة مختصرة :
      We present a case of a patient with cutaneous T-cell lymphoma started on bexarotene 300 mg/m(2) due to progressing disease. The patient experienced good clinical response, but unfortunately, she developed rapid and profound hypertriglyceridemia. Although hypertriglyceridemia occurs in high incidence with bexarotene therapy, management recommendations are scarce. Due to the rise in triglycerides, atorvastatin 10 mg daily was initiated in combination with fenofibrate 120 mg daily. Triglycerides continued to increase, so the patient was instructed to take atorvastatin 40 mg, fenofibrate 120 mg, and to hold bexarotene for 2 weeks. After the 2-week break, bexarotene was restarted at 150 mg/m(2).
    • File Description:
      application/pdf
    • Relation:
      Link to Article in PubMed; http://hdl.handle.net/20.500.14038/40653; https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4467&context=oapubs&unstamped=1; https://escholarship.umassmed.edu/oapubs/3456; oapubs/3456
    • الرقم المعرف:
      10.1159/000488447
    • الدخول الالكتروني :
      https://doi.org/10.1159/000488447
      https://hdl.handle.net/20.500.14038/40653
      https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=4467&context=oapubs&unstamped=1
      https://escholarship.umassmed.edu/oapubs/3456
    • Rights:
      © 2018 The Author(s). This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. ; http://creativecommons.org/licenses/by-nc/4.0/
    • الرقم المعرف:
      edsbas.83B6B9F2