In vivo and in silico experimental setups.

a: Incision site on the minipig. (adapted from [ 28 ] under a CC-BY 4.0 license). b: Schematic of the VN. c: Photo taken during surgery, showing the recording electrode on the VN. d-e: VN model with stimulation electrode in horizontal (d) and vertical (e) orientations. Note that the histology-based cross section topology likely differs from that of the experimentally stimulated nerve (different minipigs). In the horizontal orientation, the insulating substrate (green element in subpanel e) is not included, to avoid piercing fascicles. As all stimulus contacts (black rectangles) are active, this does not significantly influence the E-field. f: VN model with recording cuff electrode. Recording contacts (blue) are surrounded by insulation (green).