نبذة مختصرة : Cryptococcosis remains a significant opportunistic infection in solid organ transplant recipients. Disease presentation and outcomes may be affected by, among other factors, the use of calcineurin inhibitor immunosuppressive agents. It is being increasingly recognized that rapid reversal of immunosuppression in transplant recipients treated for cryptococcosis incurs the risk of immune reconstitution inflammatory syndrome, which resembles worsening disease or relapse. This review summarizes the current state of knowledge regarding cryptococcosis in transplant recipients and highlights areas where future investigations are needed to further optimize outcomes for these patients. Invasive fungal infection is a significant complication in solid organ transplant (SOT) recipients [1–3]. Improvements in transplantation practices and wider use of antifungal prophy-laxis have led to a decrease in the overall incidence of invasive fungal infection, particularly infections due to Candida and Aspergillus species [3–5]. The trends in the incidence of cryp-tococcosis among transplant recipients are less well delineated, despite ongoing surveillance in some countries [6]. However, it is plausible that major paradigm shifts in the approach to
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