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Peripheral venous catheter colonization after skin disinfection with 0.5% aqueous sodium hypochlorite, preceded or not by one application of 70% ethanol (DACLEAN): a single-centre, randomized, open-label, pilot study

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  • معلومة اضافية
    • Contributors:
      Centre hospitalier universitaire de Poitiers = Poitiers University Hospital (CHU de Poitiers La Milétrie ); Pharmacologie des anti-infectieux et antibiorésistance U 1070 (PHAR2 Poitiers ); Université de Poitiers = University of Poitiers (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM); Université de Poitiers – UFR Santé Faculté de Médecine et de Pharmacie (UFR Santé Poitiers ); Université de Poitiers = University of Poitiers (UP); MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE); Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Nantes Université - UFR des Sciences Pharmaceutiques et Biologiques (Nantes Univ - UFR Pharmacie); Nantes Université - pôle Santé; Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé; Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ); Cooper®, the manufacturer of the 0.5% sodium hypochlorite solutions and 70% modified alcohol used in the study, provided an unrestricted grant and solution samples for the study.
    • بيانات النشر:
      CCSD
      WB Saunders
    • الموضوع:
      2022
    • Collection:
      Université de Poitiers: Publications de nos chercheurs.ses (HAL)
    • نبذة مختصرة :
      International audience ; Few data are available on the efficacy of 0.5% aqueous sodium hypochlorite (SH) for skin disinfection before peripheral catheter insertion. A total of 239 patients were randomly assigned to either one application of SH alone or one application of SH preceded by one application of 70% ethanol (ET-SH). Catheter colonization, defined as a catheter tip culture growing >1000 cfu of a micro-organism per millilitre, occurred in 29 patients (33% of 89 colonizations per 1000 catheter-days) in the SH group and in 31 patients (33% of 126 colonizations per 1000 catheter-days) in the ET-SH group.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/34822950; PUBMED: 34822950
    • الرقم المعرف:
      10.1016/j.jhin.2021.11.012
    • الدخول الالكتروني :
      https://hal.science/hal-03615774
      https://hal.science/hal-03615774v1/document
      https://hal.science/hal-03615774v1/file/1-s2.0-S0195670121004102-main.pdf
      https://doi.org/10.1016/j.jhin.2021.11.012
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.6E8B619C