نبذة مختصرة : Allergic children with respiratory infections (RI) are a demanding challenge for the paediatrician. Antibiotic prescription represents a critical problem, mainly concerning the growing issue of resistance. To prevent RI would be therefore a goal in clinical practice. In this regard, modulation of immune system may have a critical role. e aim of the present study was to measure the number of respiratory infections and the use of antibiotics in two groups of children su ering from allergic rhinoconjunctivitis. e rst group took a course of a nutraceutical (Lertal®) before the observation (active group, AG); a second one was considered as control (control group, CG). e children were visited at baseline and after 1 year. e number of RI and of antibiotic courses was the primary outcomes. Children in AG reported a signi cant reduced number of RI and of antibiotic course in comparison with CG (p=0.01 and 0.002 respectively). In conclusion, the current study showed that a course with a multicomponent nutraceutical could reduce the number of respiratory infections and consequently the use of antibiotics in children with allergic rhinoconjunctivitis. (www.actabiomedica.it)
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