نبذة مختصرة : Introduction: Ayurveda has emphasized on being healthy by not only what we eat but also how we digest it. So utmost significance is given to Agni. The ancient science signifies the root cause of all metabolic disorder is imbalance of Agni told in terms of “Sarve Roga Api Mandagni”. Deepana Pachana (Appetizers and digestants) herbs are playing crucial role in treating any metabolic disease. The Gut Microbiota is collection of good bacteria, fungi, archaea and is key to many aspects to maintain Human health, builds up immunity, regulates metabolism and control neurobehavioral traits. The alteration in this Gut flora can lead to various metabolic disorders from Obesity to Cancer. Restoring the same with diet, probiotics, prebiotics and medicine is crucial for prevention and treatment for all these metabolic disorders. This review of Paper aims to identify the effect of Deepana, Pachana herbs on Gut microbiota. Materials and Methods: Literature search was done in classical text of Ayurveda for Deepana and Pachana herbs. Relevant Database for gut microbiota and relevant research articles on herbs on gut microbiota were chosen and reviewed. Result and Discussion: The review clarified that most of herbs that have Deepan, Pachana property have got Gut modulation effect and most of herbs have shown prebiotic potential gaining improvement in a positive gut bacterial alteration. Conclusion: This gut modulation effect of herbs can be used to prevent obesity, Diabetes, Cardiovascular diseases, maximizing our Health and Immunity.
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