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Elevated matrix metalloproteinases offer novel insight into their role in pediatric tuberculous meningitis

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Wellcome Trust
    • بيانات النشر:
      Oxford University Press (OUP)
    • الموضوع:
      2018
    • Collection:
      Imperial College London: Spiral
    • نبذة مختصرة :
      We collected lumbar and ventricular cerebrospinal fluid and serum from 40 children treated for tuberculous meningitis and measured the concentrations of gelatinases and their inhibitors. The concentrations of matrix metalloproteinase 9 (MMP-9), MMP-2, tissue inhibitor of metalloproteinase 1 (TIMP-1), and TIMP-2 were significantly elevated in the lumbar CSF samples, and we found interesting dynamics for MMP-9 that offer novel insight into its role in pediatric patients with tuberculous meningitis.
    • ISSN:
      2048-7193
    • Relation:
      Journal of the Pediatric Infectious Diseases Society; http://hdl.handle.net/10044/1/66737; 104803/Z/14/Z
    • الرقم المعرف:
      10.1093/jpids/piy141
    • Rights:
      © The Author(s) 2019. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
    • الرقم المعرف:
      edsbas.3BD3CEF