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A. Representative confocal microscopy images of corneal nerves labeled with β-tubulin III (green) in WT mice treated with 0.5% bupivacaine (BUP) via subconjunctival injection (SCI) alone or in combination with topical (TOP) application, as well as PBS-treated controls receiving similar subconjunctival and topical applications. Corneal tissues were processed on day 15 post-injection. Scale bar = 70 µm. B. Quantification of corneal nerve density using a grading scale (0–10) assessed by a blinded researcher in WT mice across different treatment groups.

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  • معلومة اضافية
    • الموضوع:
      2025
    • Collection:
      Federation University Australia: Figshare
    • نبذة مختصرة :
      A significant reduction in corneal nerve density was observed in mice treated with 0.5% bupivacaine (subconjunctival alone or in combination with topical application) compared to PBS-treated controls. Data are presented as mean ± SD. ** P < 0.01, **** P < 0.0001 (One-way ANOVA with Tukey’s multiple comparisons test).
    • الرقم المعرف:
      10.1371/journal.pone.0329112.g002
    • الدخول الالكتروني :
      https://doi.org/10.1371/journal.pone.0329112.g002
      https://figshare.com/articles/figure/A_Representative_confocal_microscopy_images_of_corneal_nerves_labeled_with_-tubulin_III_green_in_WT_mice_treated_with_0_5_bupivacaine_BUP_via_subconjunctival_injection_SCI_alone_or_in_combination_with_topical_TOP_application_as_well_as_PBS-/29822521
    • Rights:
      CC BY 4.0
    • الرقم المعرف:
      edsbas.3880360A