نبذة مختصرة : Chronic obstructive pulmonary disease (COPD) is characterized by persistent and usually progressive airflow limitation associated with various risk factors, the main one being tobacco smoking. The increasing role of this pathology among the causes of morbidity and mortality is well known. It should be noted that in recent years there has been a greater understanding of the complexity of this disease in terms of an integrated clinical assessment of severity, pathophysiology and relationship with other pathologies. Chronic obstructive pulmonary disease is a disease of the second half of life and a typical COPD patient suffers from an average of 4 or more concomitant diseases and every day about a third of patients take from 5 to 10 different drugs [5, 6]. In this regard, the significance of concomitant pathology for the course of COPD is important.
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