Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

EMPLOYMENT OF A «SIDE POPULATION» APPROACH TO STEM CELL ISOLATION IN NORMAL AND TUMOR TISSUES ; ИСПОЛЬЗОВАНИЕ «SIDE POPULATION» ДЛЯ ВЫДЕЛЕНИЯ СТВОЛОВЫХ КЛЕТОК В НОРМАЛЬНЫХ И ОПУХОЛЕВЫХ ТКАНЯХ

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • بيانات النشر:
      SPb RAACI
    • الموضوع:
      2014
    • Collection:
      Medical Immunology (E-Journal) / Медицинская иммунология
    • نبذة مختصرة :
      A combination of fluorescent staining with Hoechst 33342 dye, and flow cytometry of murine bone marrow cells may be used for separation of a side population (SP), which is highly enriched for hematopoietic stem cells capable of long-term hematopoietic reconstitution in lethally irradiated recipients. Recently, this approach was also applied to analysis of SP cells in several types of non-hematopoietic tissues, and malignant tumours. In spite of yet poor definition of phenotype and functional potency of SP cells from various tissues, the method of SP isolation may be a useful tool for analysis and pre-enrichment of stem cell-like cells of different origin. Present review article presents a brief description of Hoechst 33342-staining approach, and of recent reports concerning SP studies in various normal and malignant tissues. (Med. Immunol., vol. 10, N 4-5, pp 319-326). ; Резюме. Анализ клеток костного мозга мышей, окрашенного флуоресцентным красителем Hoechst 33342, на проточном цитометре позволяет выявить side population (SP), которая в значительной степени обогащена гемопоэтическими стволовыми клетками, способными полностью восстанавливать кроветворение у летально облученных реципиентов. В последние годы эта методика также использовалась для анализа клеток SP в некроветворных тканях и злокачественных опухолях. Хотя фенотип и функции SP во многих тканях до конца не изучены, методика выделения SP может быть полезна для анализа и получения популяций клеток, обладающих свойствами стволовых. В данном обзоре приводится краткое описание методики и анализируются исследования SP в нормальных и опухолевых тканях.
    • File Description:
      application/pdf
    • Relation:
      https://www.mimmun.ru/mimmun/article/view/179/181; Adams J.M., Strasser A. Is tumor growth sustained by rare cancer stem cells or dominant clones? // Cancer Res. – 2008. – Vol. 68. – P. 4018-4021.; Arai F., Hirao A., Ohmura M., Sato H., Matsuoka S., Takubo K., Ito K., Koh G.Y., Suda T. Tie2/angiopoietin-1 signaling regulates hematopoietic stem cell quiescence in the bone marrow niche // Cell. – 2004. – Vol. 118. – P. 149-161.; Bonnet D., Dick J.E. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell // Nat. Med. – 1997. – Vol. 3. – P. 730-737.; Burkert J., Otto W.R., Wright N.A. Side populations of gastrointestinal cancers are not enriched in stem cells // J. Pathol. – 2008. – Vol. 214. – P. 564-573.; Cabana R., Frolova E.G., Kapoor V., Thomas R.A., Krishan A., Telford W.G. The minimal instrumentation requirements for Hoechst side population analysis: stem cell analysis on low-cost flow cytometry platforms // Stem Cells. – 2006. – Vol. 24. – P. 2573-2581.; Camargo F.D., Chambers S.M., Drew E., McNagny K.M., Goodell M.A. Hematopoietic stem cells do not engraft with absolute efficiencies // Blood. – 2006. – Vol. 107. – P. 501-507.; Challen G.A., Little M.H. A side order of stem cells: the SP phenotype // Stem Cells. – 2006. – Vol. 24. – P. 3-12.; Engelmann K., Shen H., Finn O.J. MCF7 side population cells with characteristics of cancer stem/progenitor cells express the tumor antigen MUC1 // Cancer Res. – 2008. – Vol. 68. – P. 2419-2426.; Goodell M.A., Brose K., Paradis G., Conner A.S., Mulligan R.C. Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo // J. Exp. Med. – 1996. – Vol. 183. – P. 17971806.; Goodell M.A., Rosenzweig M., Kim H., Marks D.F., DeMaria M., Paradis G., Grupp S.A., Sieff C.A., Mulligan R.C., Johnson R.P. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species // Nat. Med. – 1997. – Vol. 3. – P. 1337-1345.; Haraguchi N., Utsunomiya T., Inoue H., Tanaka F., Mimori K., Barnard G.F., Mori M. Characterization of a side population of cancer cells from human gastrointestinal system // Stem Cells. – 2006. – Vol. 24. – P. 506-513.; Hiddemann W., Roessner A., Wormann B., Mellin W., Klockenkemper B., Bosing T., Buchner T., Grundmann E. Tumor heterogeneity in osteosarcoma as identified by flow cytometry // Cancer. – 1987. – Vol. 59. – P. 324-328.; Hill R.P. Identifying cancer stem cells in solid tumors: case not proven // Cancer Res. – 2006. – Vol. 66. – P. 1891-1895; discussion 1890.; Hirschmann-Jax C., Foster A.E., Wulf G.G., Nuchtern J.G., Jax T.W., Gobel U., Goodell M.A., Brenner M.K. A distinct «side population» of cells with high drug efflux capacity in human tumor cells // Proc. Natl. Acad. Sci. U S A. – 2004. – Vol. 101. – P. 14228-14233.; Ho M.M., Ng A.V., Lam S., Hung J.Y. Side population in human lung cancer cell lines and tumors is enriched with stem-like cancer cells // Cancer Res. – 2007. – Vol. 67. – P. 4827-4833.; Jonker J.W., Freeman J., Bolscher E., Musters S., Alvi A.J.,Titley I., Schinkel A.H., Dale T.C. Contribution of the ABC transporters Bcrp1 and Mdr1a/1b to the side population phenotype in mammary gland and bone marrow of mice // Stem Cells. – 2005. – Vol. 23. – P. 1059-1065.; Julius M.H., Masuda T., Herzenberg L.A. Demonstration that antigen-binding cells are precursors of antibody-producing cells after purification with a fluorescence-activated cell sorter // Proc. Natl. Acad. Sci. U S A. – 1972. – Vol. 69. – P. 1934-1938.; Kato K., Yoshimoto M., Kato K., Adachi S., Yamayoshi A., Arima T., Asanoma K., Kyo S., Nakahata T., Wake N. Characterization of side-population cells in human normal endometrium // Hum. Reprod. – 2007. – Vol. 22. – P. 1214-1223.; Kawanabe N., Murakami K., Takano-Yamamoto T. The presence of ABCG2-dependent side population cells in human periodontal ligaments // Biochem. Biophys. Res. Commun. – 2006. – Vol. 344. – P. 1278-1283.; Kelly P.N., Dakic A., Adams J.M., Nutt S.L., Strasser A. Tumor growth need not be driven by rare cancer stem cells // Science. – 2007. – Vol. 317. – P. 337.; Kern S.E., Shibata D. The fuzzy math of solid tumor stem cells: a perspective // Cancer Res. – 2007. – Vol. 67. – P. 8985-8988.; Kobayashi I., Moritomo T., Ototake M., Nakanishi T. Isolation of side population cells from ginbuna carp (Carassius auratus langsdorfii) kidney hematopoietic tissues // Dev. Comp. Immunol. – 2007. – Vol. 31. – P. 696-707.; Kondo M., Wagers A.J., Manz M.G., Prohaska S.S., Scherer D.C., Beilhack G.F., Shizuru J.A., Weissman I.L. Biology of hematopoietic stem cells and progenitors: implications for clinical application // Annu. Rev. Immunol. – 2003. – Vol. 21. – P. 759-806.; Kondo T., Setoguchi T., Taga T. Persistence of a small subpopulation of cancer stem-like cells in the C6 glioma cell line // Proc. Natl. Acad. Sci. USA. – 2004. – Vol. 101. – P. 781-786.; Larderet G., Fortunel N.O., Vaigot P., Cegalerba M., Maltere P., Zobiri O., Gidrol X., Waksman G., Martin M.T. Human side population keratinocytes exhibit long- term proliferative potential and a specific gene expression profile and can form a pluristratified epidermis // Stem Cells. – 2006. – Vol. 24. – P. 965-974.; Lechner A., Leech C.A., Abraham E.J., Nolan A.L. Habener J.F. Nestin-positive progenitor cells derived from adult human pancreatic islets of Langerhans contain side population (SP) cells defined by expression of the ABCG2 (BCRP1) ATP-binding cassette transporter // Biochem. Biophys. Res. Commun. – 2002. – Vol. 293. – P. 670-674.; Martin C.M., Meeson A.P., Robertson S.M., Hawke T.J., Richardson J.A., Bates S., Goetsch S.C., Gallardo T.D., Garry D.J. Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart // Dev. Biol. – 2004. – Vol. 265. – P. 262-275.; Maximow A. Der Lymphozyt als gemeinsane Stammzelle der verschiedenen Blutelemente in der embryonalen Entwicklung und im postfetalen Leben der S ugefiere // Sitzungsb. Berl. H matol. Gesellsch. – 1910. – Vol. 10. – P. 86-95.; Montanaro F., Liadaki K., Schienda J., Flint A., Gussoni E., Kunkel L.M. Demystifying SP cell purification: viability, yield, and phenotype are defined by isolation parameters // Exp. Cell Res. – 2004. – Vol. 298. – P. 144-154.; Reya T., Morrison S.J., Clarke M.F., Weissman I.L. Stem cells, cancer, and cancer stem cells // Nature. – 2001. – Vol. 414. – P. 105-111.; Sales-Pardo I., Avendano A., Martinez-Munoz V., Garcia-Escarp M., Celis R., Whittle P., Barquinero J., Domingo J.C., Marin P., Petriz J. Flow cytometry of the Side Population: tips & tricks // Cell Oncol. – 2006. – Vol. 28. – P. 37-53.; Shi G.M., Xu Y., Fan J., Zhou J., Yang X.R., Qiu S.J., Liao Y., Wu W.Z., Ji Y., Ke A.W., Ding Z.B., He Y.Z., Wu B., Yang G.H., Qin W.Z., Zhang W., Zhu J., Min Z.H., Wu Z.Q. Identification of side population cells in human hepatocellular carcinoma cell lines with stepwise metastatic potentials // J. Cancer Res. Clin. Oncol. – 2008.; Simpson C., Pearce D.J., Bonnet D., Davies D. Out of the blue: a comparison of Hoechst side population (SP) analysis of murine bone marrow using 325, 363 and 407 nm excitation sources // J. Immunol. Methods. – 2006. – Vol. 310. – P. 171-181.; Spangrude G.J., Heimfeld S., Weissman I.L. Purification and characterization of mouse hematopoietic stem cells // Science. – 1988. – Vol. 241. – P. 58-62.; Sung J.M., Cho H.J., Yi H., Lee C.H., Kim H.S., Kim D.K., Abd El-Aty A.M., Kim J.S., Landowski C.P., Hediger M.A., Shin H.C. Characterization of a stem cell population in lung cancer A549 cells // Biochem. Biophys. Res. Commun. – 2008. – Vol. 371. – P. 163-167.; Szotek P.P., Pieretti-Vanmarcke R., Masiakos P.T., Dinulescu D.M., Connolly D., Foster R., Dombkowski D., Preffer F., Maclaughlin D.T., Donahoe P.K. Ovarian cancer side population defines cells with stem cell-like characteristics and Mullerian Inhibiting Substance responsiveness // Proc. Natl. Acad. Sci. USA. – 2006. – Vol. 103. – P. 11154-11159.; Telford W.G., Bradford J., Godfrey W., Robey R.W., Bates S.E. Side population analysis using a violet-excited cell-permeable DNA binding dye // Stem Cells. – 2007. – Vol. 25. – P. 1029-1036.; Telford W.G., Frolova E.G. Discrimination of the Hoechst side population in mouse bone marrow with violet and near-ultraviolet laser diodes // Cytometry A. – 2004. – Vol. 57. – P. 45-52.; Till J.E., McCulloch E.A. A direct measurement of the radiation sensitivity of normal mouse bone marrow cells // Radiat. Res. – 1961. – Vol. 14. – P. 213-222.; Tsinkalovsky O., Filipski E., Rosenlund B., So thern R.B., Eiken H.G., Wu M.W., Claustrat B., Bayer J., Levi F., Laerum O.D. Circadian expression of clock genes in purified hematopoietic stem cells is developmentally regulated in mouse bone marrow // Exp. Hematol. – 2006. – Vol. 34. – P. 1249-1261.; Tsinkalovsky O., Rosenlund B., Laerum O.D., Eiken H.G. Clock gene expression in purified mouse hematopoietic stem cells // Exp. Hematol. – 2005. – Vol. 33. – P. 100-107.; Tsinkalovsky O., Vik-Mo A.O., Ferreira S., Laerum O.D., Fjose A. Zebrafish kidney marrow contains ABCG2-dependent side population cells exhibiting hematopoietic stem cell properties // Differentiation. – 2007. – Vol. 75. – P. 175-183.; Venezia T.A., Merchant A.A., Ramos C.A., Whitehouse N.L., Young A.S., Shaw C.A., Goodell M.A. Molecular signatures of proliferation and quiescence in hematopoietic stem cells // PLoS Biol. – 2004. – Vol. 2. – P. e301.; Wang J., Sakariassen P.O., Tsinkalovsky O., Immervoll H., Boe S.O., Svendsen A., Prestegarden L., Rosland G., Thorsen F., Stuhr L., Molven A., Bjerkvig R., Enger P.O. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells // Int. J. Cancer. – 2008. – Vol. 122. – P. 761-768.; Wang J.C., Dick J.E. Cancer stem cells: lessons from leukemia // Trends Cell Biol. – 2005. – Vol. 15. – P. 494-501.; Weissman I.L. The road ended up at stem cells // Immunol. Rev. – 2002. – Vol. 185. – P. 159-174.; Weissman I.L. Normal and neoplastic stem cells // Novartis Found Symp. – 2005. – Vol. 265. – P. 35-50; discussion 50-34, 92-37.; Weissman I.L., Anderson D.J., Gage F. Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations // Annu. Rev. Cell Dev. Biol. – 2001. – Vol. 17. – P. 387-403.; Wu C., Alman B.A. Side population cells in human cancers // Cancer Lett. – 2008.; Wu C., Wei Q., Utomo V., Nadesan P., Whetstone H., Kandel R., Wunder J.S., Alman B.A. Side population cells isolated from mesenchymal neoplasms have tumor initiating potential // Cancer Res. – 2007. – Vol. 67. – P. 8216-8222.; Yamahara K., Fukushima S., Coppen S.R., Felkin L.E., Varela-Carver A., Barton P.J., Yacoub M.H., Suzuki K. Heterogeneic nature of adult cardiac side population cells // Biochem. Biophys. Res. Commun. – 2008. – Vol. 371. – P. 615-620.; Zheng X., Shen G., Yang X., Liu W. Most C6 cells are cancer stem cells: evidence from clonal and population analyses // Cancer Res. – 2007. – Vol. 67. – P. 3691-3697.; Zhou S., Schuetz J.D., Bunting K.D., Colapi-etro A.M., Sampath J., Morris J.J., Lagutina I., Grosveld G.C., Osawa M., Nakauchi H., Sorrentino B.P. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype // Nat. Med. – 2001. – Vol. 7. – P. 1028-1034.; https://www.mimmun.ru/mimmun/article/view/179
    • الرقم المعرف:
      10.15789/1563-0625-2008-4-5-319-326
    • الدخول الالكتروني :
      https://www.mimmun.ru/mimmun/article/view/179
      https://doi.org/10.15789/1563-0625-2008-4-5-319-326
    • Rights:
      Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). ; Авторы, публикующие в данном журнале, соглашаются со следующим:Авторы сохраняют за собой авторские права на работу и предоставляют журналу право первой публикации работы на условиях лицензии Creative Commons Attribution License, которая позволяет другим распространять данную работу с обязательным сохранением ссылок на авторов оригинальной работы и оригинальную публикацию в этом журнале.Авторы сохраняют право заключать отдельные контрактные договорённости, касающиеся не-эксклюзивного распространения версии работы в опубликованном здесь виде (например, размещение ее в институтском хранилище, публикацию в книге), со ссылкой на ее оригинальную публикацию в этом журнале.Авторы имеют право размещать их работу в сети Интернет (например в институтском хранилище или персональном сайте) до и во время процесса рассмотрения ее данным журналом, так как это может привести к продуктивному обсуждению и большему количеству ссылок на данную работу (См. The Effect of Open Access).
    • الرقم المعرف:
      edsbas.19B4D0AB