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Impact of COVID-19 Pandemic Interventions on Sudden Unexpected Death in Infancy Incidence in France

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  • معلومة اضافية
    • Contributors:
      Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes); CIC Plurithématique de Nantes; Institut National de la Santé et de la Recherche Médicale (INSERM)-Ministère des Affaires sociales et de la Santé-Direction générale de l'offre de soins (DGOS)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes); AP-HP Hôpital universitaire Robert-Debré Paris; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); Association Clinique et Thérapeutique Infantile du Val de Marne (ACTIV); Infection, Anti-microbiens, Modélisation, Evolution (IAME (UMR_S_1137 / U1137)); Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord; Epidémiologie Clinique et Evaluation Economique Appliquées aux Populations Vulnérables (ECEVE (U1123 / UMR_S_1123)); Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital universitaire Robert-Debré Paris; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Cité (UPCité); Université Sorbonne Paris Nord
    • بيانات النشر:
      CCSD
      Elsevier
    • الموضوع:
      2025
    • Collection:
      Université Paris 13: HAL
    • نبذة مختصرة :
      International audience ; ObjectiveTo study the impact of nonpharmaceutical interventions implemented during the COVID-19 pandemic on the monthly incidence of sudden unexpected death in infancy (SUDI) cases overall and those with a viral or bacterial identification.Study designWe conducted an interrupted time-series analysis using seasonally adjusted Poisson regression models from the French national prospective and multicenter SUDI registry, that included all SUDI cases below the age of 1 year who died from 2016 to 2021 in mainland France.ResultsOf 998 SUDI cases analyzed, 750 were recorded during the prepandemic period (January 2016 through March 2020) and 248 during the NPI period (April 2020 through December 2021). We found a significant seasonal pattern of overall monthly SUDI incidence, with a peak observed periodically from November to February. The monthly SUDI incidence decreased significantly from the prepandemic to NPI periods (adjusted incidence rate ratio 0.83 [95% CI 0.72-0.96]). In particular, the monthly incidence of SUDI cases with a viral or bacterial identification decreased significantly, while no significant difference was found for SUDI cases without a viral or bacterial identification.ConclusionsNonpharmaceutical interventions were associated with a significant change in the incidence of SUDI cases with a viral or bacterial identification. Further investigations are needed to analyze the pathophysiologic role of viruses and bacteria in the SUDI.
    • الرقم المعرف:
      10.1016/j.jpeds.2024.114369
    • الدخول الالكتروني :
      https://hal.science/hal-05121297
      https://hal.science/hal-05121297v1/document
      https://hal.science/hal-05121297v1/file/1-s2.0-S0022347624004724-main.pdf
      https://doi.org/10.1016/j.jpeds.2024.114369
    • Rights:
      http://creativecommons.org/licenses/by-nc-nd/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.190817C1