Predictors of durable electrical isolation in the setting of second‐generation cryoballoon ablation: A comparison between left superior, left inferior, right superior, and right inferior pulmonary veins: A Comparison between Left Superior, Left Inferior, Right Superior and Right Inferior Pulmonary Veins

AimThe aim of this study is to assess specific per‐vein procedural predictors of pulmonary vein (PV) late reconnection in cryoballoon ablation (CbA)Methods and ResultsWe enrolled 148 consecutive patients undergoing a redo procedure after a previous index CbA in our center. A reconnection in at least one PV was found in 80 patients (54.1%) and the most frequently reconnected PV was the right inferior pulmonary vein (RIPV). Overall, pulmonary vein reconnection (PVr) was associated with longer time to −40°C (Tt−40°C) (54.4 ± 21.7 vs 67.6 ± 27.6 seconds; P P P ConclusionsFreezing behavior and reconnection rates differ significantly among the four PVs. Freezing temperature parameters strongly predict late PVr in superior PVs and are slightly different in RIPV but can be applied as well. LIPV freezing behavior is the most different. Its reconnection is uncommon even in the subset of worse freezing temperatures and specific CB predictors cannot be identified.