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Progressing nanotechnology to improve targeted cancer treatment: overcoming hurdles in its clinical implementation

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  • معلومة اضافية
    • بيانات النشر:
      Springer Science and Business Media LLC, 2023.
    • الموضوع:
      2023
    • نبذة مختصرة :
      The use of nanotechnology has the potential to revolutionize the detection and treatment of cancer. Developments in protein engineering and materials science have led to the emergence of new nanoscale targeting techniques, which offer renewed hope for cancer patients. While several nanocarriers for medicinal purposes have been approved for human trials, only a few have been authorized for clinical use in targeting cancer cells. In this review, we analyze some of the authorized formulations and discuss the challenges of translating findings from the lab to the clinic. This study highlights the various nanocarriers and compounds that can be used for selective tumor targeting and the inherent difficulties in cancer therapy. Nanotechnology provides a promising platform for improving cancer detection and treatment in the future, but further research is needed to overcome the current limitations in clinical translation. Graphical Abstract
    • ISSN:
      1476-4598
    • الرقم المعرف:
      10.1186/s12943-023-01865-0
    • الرقم المعرف:
      10.60692/j1ve6-xf315
    • الرقم المعرف:
      10.60692/4bf0a-8xh05
    • الرقم المعرف:
      10.15496/publikation-95645
    • Rights:
      CC BY
      URL: http://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (http://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (http://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
    • الرقم المعرف:
      edsair.doi.dedup.....4d21a9d23f0c4ce42276f7fec88df378