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Molecular Analysis of Emerging MT27 Macrolide-Resistant Bordetella pertussis, Kobe, Japan, 2025.

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  • معلومة اضافية
    • المصدر:
      Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
    • الموضوع:
      Bordetella pertussis*/genetics ; Bordetella pertussis*/drug effects ; Bordetella pertussis*/classification ; Macrolides*/pharmacology ; Whooping Cough*/epidemiology ; Whooping Cough*/microbiology ; Whooping Cough*/history ; Anti-Bacterial Agents*/pharmacology ; Drug Resistance, Bacterial*/genetics; Japan/epidemiology ; Humans ; Minisatellite Repeats ; Microbial Sensitivity Tests ; Whole Genome Sequencing ; Multilocus Sequence Typing
    • نبذة مختصرة :
      We report the emergence and spread of multilocus variable-number tandem-repeat analysis type 27 (MT-27) macrolide-resistant Bordetella pertussis (MRBP) in Kobe, Japan, in 2025. Whole-genome sequencing revealed that MT27-MRBP did not originate from the widely circulating MT27 macrolide-sensitive B. pertussis in Japan but was closely related to MRBP in China.
    • References:
      J Glob Antimicrob Resist. 2022 Dec;31:263-269. (PMID: 36270447)
      Front Microbiol. 2022 Jul 18;13:901617. (PMID: 35923401)
      Microbiol Spectr. 2023 Jun 15;11(3):e0406522. (PMID: 37191540)
      J Infect Chemother. 2025 Jul;31(7):102727. (PMID: 40348379)
      Clin Microbiol Infect. 2024 Nov;30(11):1439-1446. (PMID: 39209267)
      Front Immunol. 2025 Jul 10;16:1618883. (PMID: 40709171)
      Int J Infect Dis. 2025 Sep;158:107960. (PMID: 40541771)
      PLoS One. 2024 Feb 15;19(2):e0298147. (PMID: 38359004)
      Antibiotics (Basel). 2022 Nov 07;11(11):. (PMID: 36358225)
    • Contributed Indexing:
      Keywords: Bordetella pertussis; Japan; MRBP; MT27; antimicrobial resistance; bacteria; macrolide-resistant Bordetella pertussis; prn150
    • الرقم المعرف:
      0 (Macrolides)
      0 (Anti-Bacterial Agents)
    • الموضوع:
      Date Created: 20260130 Date Completed: 20260130 Latest Revision: 20260206
    • الموضوع:
      20260206
    • الرقم المعرف:
      PMC12872074
    • الرقم المعرف:
      10.3201/eid3201.250890
    • الرقم المعرف:
      41612627