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Inspection confirmed mold damage in schools and new use of drugs for airway obstruction: A cohort study.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: San Francisco, CA : Public Library of Science
    • الموضوع:
      Schools* ; Fungi*/isolation & purification ; Asthma*/drug therapy ; Asthma*/epidemiology ; Asthma*/microbiology ; Asthma*/etiology ; Airway Obstruction*/drug therapy ; Airway Obstruction*/microbiology ; Airway Obstruction*/epidemiology ; Air Pollution, Indoor*/adverse effects ; Air Pollution, Indoor*/analysis; Humans ; Finland/epidemiology ; Female ; Male ; Child ; Adolescent ; Cohort Studies ; Students
    • نبذة مختصرة :
      Competing Interests: The authors have declared that no competing interests exist.
      Objective: To test if extent and severity of mold damage in school buildings increases the risk of new use of drugs for airway obstruction among students with a dose-response.
      Methods: Extent of mold damage in 110 Finnish primary and secondary school buildings in 2004 was estimated based on all technical inspections done by 2021. New asthma (n = 1,035) and use of drugs for obstructive airway diseases (n = 3,162) among 30,418 students by 2019 was defined based on drug purchases. Multilevel Cox models were adjusted for confounders obtained from Medical Birth Register.
      Results: Extensive mold damage was common. Nine buildings had no or small mold damage, 19 buildings limited, 44 wide and 38 very wide damage in 2004. No association with onset of asthma was observed neither in all students nor in students with previous obstructive airway problems. Among primary school students, there was some suggestion for an association with new use of drugs for obstructive airway diseases, but with highest risk in buildings with limited damage.
      Conclusions: The results from this unique and large follow-up study suggest that assessment of the extent and severity of mold damage inside building structures in Finnish schools do not identify buildings, in which students are at increased risk of developing asthma.
      (Copyright: © 2025 Pekkanen et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
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    • الموضوع:
      Date Created: 20251008 Date Completed: 20251008 Latest Revision: 20251011
    • الموضوع:
      20251011
    • الرقم المعرف:
      PMC12507237
    • الرقم المعرف:
      10.1371/journal.pone.0333486
    • الرقم المعرف:
      41061024