Visual Volatile-Compound Fingerprint Based on Headspace Gas Chromatography-Ion Mobility Spectrometry Combined with Chemometrics Analysis and Exploration in the Authentic Identification of Lonicerae japonicae flos.

Publisher: Oxford University Press Country of Publication: United States NLM ID: 0173225 Publication Model: Print Cited Medium: Internet ISSN: 1945-239X (Electronic) Linking ISSN: 00219665 NLM ISO Abbreviation: J Chromatogr Sci Subsets: MEDLINE

Publication: <2012- > : Oxford : Oxford University Press
Original Publication: Niles Il : Preston Technical Abstracts

Lonicera*/chemistry ; Volatile Organic Compounds*/analysis; Gas Chromatography-Mass Spectrometry/methods ; Chemometrics ; Ion Mobility Spectrometry/methods ; Ketones/analysis

Headspace gas chromatography-ion mobility spectrometric (HS-GC-IMS) fingerprint of volatile organic compounds (VOCs) in Lonicerae japonicae flos (LJF, Jinyinhua in Chinese) was developed. This method, combined with chemometrics analysis, was explored in the identification of authentic LJF. Seventy VOCs were identified from LJF, including aldehydes, ketones, esters, etc. The developed volatile-compound fingerprint based on HS-GC-IMS coupled with PCA analysis can successfully discriminate LJF from its adulterant: Lonicerae japonicae(LJ, called Shanyinhua in China) and can equally discriminate the LJF samples from different geographical origins of China. Total of four (compound 120, compound 184, 2-heptanone and 2-heptanone#2) and nine VOCs (styrene, compound 41, 3z-hexenol, methylpyrazine, hexanal#2, compound 78, compound 110, compound 124 and compound 180) were exploited, which might serve as the chemical markers for the difference of LJF, LJ and LJF from different regions of China. The result showed that the fingerprint based on HS-GC-IMS combined with PCA exhibited distinct advantages, such as rapid, intuitive and powerful selectivity, which demonstrated great application potential in the authentic identification of LJF.
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2021CXGC010508 Shandong Major Technological Innovation Project; 2060302 Key Project at Central Government Level; 2020GXRC007 Innovative Team of Jinan; 2022JBZ02-04 Science, Education and Industry Integration Innovation Pilot Project from Qilu University of Technology

89VVP1B008 (2-heptanone)
0 (Ketones)
0 (Volatile Organic Compounds)

Date Created: 20230309 Date Completed: 20230428 Latest Revision: 20230428

20250114

10.1093/chromsci/bmad015

36892165