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Pathology interface for the molecular analysis of tissue by mass spectrometry.

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اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • المصدر:
      Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101528849 Publication Model: eCollection Cited Medium: Print ISSN: 2229-5089 (Print) NLM ISO Abbreviation: J Pathol Inform Subsets: PubMed not MEDLINE
    • بيانات النشر:
      Publication: 2022- : [New York] : Elsevier Inc.
      Original Publication: Ghatkopar, Mumbai : Medknow Publications and Media, 2010-
    • نبذة مختصرة :
      Background: Imaging mass spectrometry (IMS) generates molecular images directly from tissue sections to provide better diagnostic insights and expand the capabilities of clinical anatomic pathology. Although IMS technology has matured over recent years, the link between microscopy imaging currently used by pathologists and MS-based molecular imaging has not been established.
      Methods: We adapted the Vanderbilt University Tissue Core workflow for IMS into a web-based system that facilitates remote collaboration. The platform was designed to perform within acceptable web response times for viewing, annotating, and processing high resolution microscopy images.
      Results: We describe a microscopy-driven approach to tissue analysis by IMS.
      Conclusion: The Pathology Interface for Mass Spectrometry is designed to provide clinical access to IMS technology and deliver enhanced diagnostic value.
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    • Grant Information:
      P41 GM103391 United States GM NIGMS NIH HHS
    • Contributed Indexing:
      Keywords: Diagnostics; imaging mass spectrometry; molecular imaging
    • الموضوع:
      Date Created: 20160504 Date Completed: 20160504 Latest Revision: 20220729
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC4837791
    • الرقم المعرف:
      10.4103/2153-3539.179903
    • الرقم المعرف:
      27141319