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Granular cell tumor of the breast: a case report.

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  • معلومة اضافية
    • المصدر:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101293382 Publication Model: Electronic Cited Medium: Internet ISSN: 1752-1947 (Electronic) Linking ISSN: 17521947 NLM ISO Abbreviation: J Med Case Rep Subsets: MEDLINE
    • بيانات النشر:
      Original Publication: [London] : BioMed Central, [2007-
    • الموضوع:
      Mammography* ; Ultrasonography, Mammary*; Breast Neoplasms/*pathology ; Granular Cell Tumor/*pathology; Adult ; Breast Neoplasms/surgery ; Diagnosis, Differential ; Female ; Granular Cell Tumor/surgery ; Humans ; Immunohistochemistry ; Treatment Outcome ; Unnecessary Procedures
    • نبذة مختصرة :
      Introduction: A granular cell tumor involving the breast parenchyma was first described by Abrikossoff in 1931. Localization of this lesion to the breast is very rare, accounting for between 5% and 15% of all granular cell tumor cases. We present this case because of the rarity of this tumor. It is frequently confused with breast carcinoma on clinical and radiological examination, and its diagnosis can therefore be challenging for clinicians, radiologists and pathologists.
      Case Presentation: We report the case of a 32-year-old Moroccan woman who presented with a palpable mass in her right breast. Mammography and ultrasound examination revealed a heterogeneous, irregular and poorly limited mass, located at the union of the outer quadrants of her right breast. The mass was in contact with her latissimus dorsi and suspicious for malignancy. A histological examination combined with immunohistochemical study revealed it to be a granular cell tumor.
      Conclusion: Although a granular cell tumor of the breast is a rare breast neoplasm, it should be considered in the differential diagnosis of benign and malignant lesions. Pathologists should bear in mind a granular cell tumor when examining material containing cells with abundant granular cytoplasm to avoid misdiagnosing breast carcinoma, which could lead to unnecessary surgery.
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    • الموضوع:
      Date Created: 20141227 Date Completed: 20150924 Latest Revision: 20181113
    • الموضوع:
      20250114
    • الرقم المعرف:
      PMC4307888
    • الرقم المعرف:
      10.1186/1752-1947-8-465
    • الرقم المعرف:
      25541096