中国中老年人社会隔离与衰弱的纵向关联研究.

Longitudinal association between social isolation and frailty in Chinese middle - aged and older adults.

Objective To explore the relationship between social isolation and frailty trajectories, and to provide evidence for targeted interventions and healthy aging. Methods Based on four waves (2011 -2018) of the China Health and Retirement Longitudinal Study, 7 805 adults aged 45 years and above were included. Latent Class Mixed Models (LCMM) wereapplied to identify longitudinal trajectories of social isolation and the frailty index. Multinomial logistic regression was used to analyze factors associated with each trajectory, and conditional and joint probabilities were calculated to evaluate the correspondence between social isolation and frailty trajectories. Results Four trajectories of social isolation were identified: Low - isolation stable (36. 0%), Low - isolation rapid increase (2, 7%), Moderate - isolation stable (52, 7%), andHigh - isolation slow increase(8. 7%)--along with three frailty trajectories: Robust stable (27. 0%), Prefrail stable (54. 2%), and Frailty worsening (18.8%). Joint probabilities further indicated that the combination of Moderate - isolation stable and Prefrail - stable had the highest overall probability (= 0. 29), Conclusion Levels and temporal patterns of social isolation are strongly associated with frailty development. Middle - aged and older adults with higher or increasing isolation levels, as well as those at the prefrail stage, should be prioritized in community - based interventions aimed at strengthening social support, maintaining physical function, and improving psychological well - being to delay frailty progression and promote healthy aging. [ABSTRACT FROM AUTHOR]

目的探讨社会隔离与衰弱轨迹的关系, 为精准干预和健康老龄化提供参考。方法基于2011 -- 2018年中国健 康与养老追踪调查（CHARLS）四期数据, 纳人7 805名中老年人, 采用潜在类别混合模型（LCMM）识别社会隔离与衰弱 指数（FI）的纵向轨迹, 运用多项logistic回归分析各轨迹的影响因素, 并计箅社会隔离与衰弱轨迹的条件概率和联合概 率。结果共i只别出社会隔离的四条轨迹--"低隔离稳定组"（36. 0% ）、"低隔离急升组"（2. 7% ）、"中度隔离稳定 组"（52.7%）和"高隔离缓升组"（8.7%）;以及衰弱的三条轨迹--"健康稳定组"（27.0%）、"衰弱前期稳定组" （54.2%）和"衰弱加重组"（18. 8% ）。双轨迹分析显示, "中度隔离稳定组"与"衰弱前期稳定组"的联合概率最高（7 = 0.29）。结论社会隔离的水平及其变化趋势与衰弱的发展轨迹存在显著关联。针对隔离水平较高或呈上升趋势 的群体, 以及处于衰弱前期阶段的中老年人, 需在社区中加强社会支持、功能维护与心理健康管理, 以延缓衰弱进展并 促进健康老龄化。. [ABSTRACT FROM AUTHOR]