Dexmedetomidine rapidly lowers symptoms of agitation in bipolar disorder.

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المؤلفون: S. H., Preskorn; S., Zeller; L., Citrome
المصدر:
Brown University Psychopharmacology Update. Jun2022, Vol. 33 Issue 6, p1-6. 3p.

معلومة اضافية
- الموضوع:
  Sublingual drug administration; Bioavailability; Agitation (Psychology); Imidazoles; Intramuscular injections; Treatment effectiveness; Olanzapine; Adverse health care events; Bipolar disorder; Antipsychotic agents
- نبذة مختصرة :
  The article reports that single dose of the alpha-2 adrenergic receptor agonist dexmedetomidine reduced symptoms of agitation within several hours in patients with bipolar disorder, a Phase 3 placebo-controlled trial found. Topics include considered that treatment effects from sublingual dexmedetomidine at two dosage strengths were observed several minutes after administration.