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  • 1-10 ل  119,298 نتائج ل ""tyrosine""

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Academic Journal

Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways.

  • Authors : Langlois J; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070, Basel, Switzerland.; Lange S

Subjects: Microglia*/Microglia*/Microglia*/drug effects ; Microglia*/Microglia*/Microglia*/metabolism ; Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors

  • Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Oct 27; Vol. 21 (1), pp. 276. Date of Electronic Publication: 2024 Oct 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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Academic Journal

Upfront Management of Blastoid Variant Mantle Cell Lymphoma: Making the Case for 2nd/3rd-Generation Bruton Tyrosine Kinase Inhibitor-Based Therapies.

  • Authors : Lee BJ; Department of Pharmacy, University of California Irvine Health, Orange, California, USA.; Department of Clinical Pharmacy Practice, School of Pharmacy & Pharmaceutical Sciences, University of California, Irvine, California, USA.

Subjects: Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/drug therapy ; Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/therapy ; Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/Lymphoma, Mantle-Cell*/mortality

  • Source: Cancer medicine [Cancer Med] 2024 Oct; Vol. 13 (19), pp. e70310.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

A Bruton tyrosine kinase inhibitor-resistance gene signature predicts prognosis and identifies TRIP13 as a potential therapeutic target in diffuse large B-cell lymphoma.

  • Authors : Ding Y; Department of Hematology/Hematological Lab, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.; Huang K

Subjects: Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/genetics ; Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/drug therapy ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Sep 11; Vol. 14 (1), pp. 21184. Date of Electronic Publication: 2024 Sep 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

MERTK Inhibition as a Targeted Novel Cancer Therapy.

  • Authors : Tanim KM; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA 30322, USA.; Department of Pediatrics, Emory University School of Medicine, Atlanta, GA 30322, USA.

Subjects: Neoplasms*/Neoplasms*/Neoplasms*/drug therapy ; Neoplasms*/Neoplasms*/Neoplasms*/metabolism ; c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 12; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Gas6 and Protein S Ligands Cooperate to Regulate MerTK Rhythmic Activity Required for Circadian Retinal Phagocytosis.

  • Authors : Parinot C; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 rue Moreau, F-75012 Paris, France.; Chatagnon J

Subjects: c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/metabolism ; c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/genetics ; Intercellular Signaling Peptides and Proteins*/Intercellular Signaling Peptides and Proteins*/Intercellular Signaling Peptides and Proteins*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 16; Vol. 25 (12). Date of Electronic Publication: 2024 Jun 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Evolving Role of Bruton's Tyrosine Kinase Inhibitors in B Cell Lymphomas.

  • Authors : Mehra S; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.; Nicholls M

Subjects: Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors ; Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/metabolism ; Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/Protein Kinase Inhibitors*/therapeutic use

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jul 09; Vol. 25 (14). Date of Electronic Publication: 2024 Jul 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Arrhythmogenic Ventricular Remodeling by Next-Generation Bruton's Tyrosine Kinase Inhibitor Acalabrutinib.

  • Authors : Zhao Y; Toronto General Hospital Research Institute, University Health Network, Toronto, ON M5G 2M1, Canada.; Chakraborty P

Subjects: Benzamides*/Benzamides*/Benzamides*/pharmacology ; Benzamides*/Benzamides*/Benzamides*/therapeutic use ; Rats, Sprague-Dawley*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jun 05; Vol. 25 (11). Date of Electronic Publication: 2024 Jun 05.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The TAM Subfamily of Receptor Tyrosine Kinases: The Early Years.

  • Authors : Prieto AL; Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN 47405, USA.; Lai C

Subjects: Axl Receptor Tyrosine Kinase* ; Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/Proto-Oncogene Proteins*/genetics; c-Mer Tyrosine Kinase/c-Mer Tyrosine Kinase/c-Mer Tyrosine Kinase/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 16; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

In the Eyes of the Beholder-New Mertk Knockout Mouse and Re-Evaluation of Phagocytosis versus Anti-Inflammatory Functions of MERTK.

  • Authors : Ghosh S; Department of Neurology, School of Medicine, Yale University, New Haven, CT 06520, USA.; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06520, USA.

Subjects: c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/metabolism ; c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/c-Mer Tyrosine Kinase*/genetics ; Phagocytosis*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 May 13; Vol. 25 (10). Date of Electronic Publication: 2024 May 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Probing the Immunoreceptor Tyrosine-Based Inhibition Motif Interaction Protein Partners with Proteomics.

  • Authors : Gao Y; School of Life Sciences, Jilin University, Changchun 130012, China.; Xing S

Subjects: Proteomics*/Proteomics*/Proteomics*/methods ; Protein Binding* ; Immunoreceptor Tyrosine-Based Inhibition Motif*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2024 Apr 25; Vol. 29 (9). Date of Electronic Publication: 2024 Apr 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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  • 1-10 ل  119,298 نتائج ل ""tyrosine""