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پیشگویی تمایل اتصال تعدادی از مشتقات ایماتینیب به عنوان مهار کننده های تیروزین کیناز بر اساس بهینه سازی مونت کارلو.

• Authors : شهرام لطفی¹; شهین احمدی² ; شراره وردست باغم³

Subjects: *THERAPEUTIC use of antineoplastic agents; *STATISTICAL correlation; *HEMATOLOGIC malignanciesIRAN

• Source: Journal of Ilam University of Medical Sciences. 2024, Vol. 32 Issue 4, p66-86. 21p.

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Upfront Management of Blastoid Variant Mantle Cell Lymphoma: Making the Case for 2nd/3rd‐Generation Bruton Tyrosine Kinase Inhibitor‐Based Therapies.

• Authors : Lee, Benjamin J.^1,2 (AUTHOR) ; Liu, Jenny¹ (AUTHOR); Griffin, Shawn P.^1,2 (AUTHOR)

• Source: Cancer Medicine. Oct2024, Vol. 13 Issue 19, p1-6. 6p.

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Fenebrutinib, a Bruton's tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways.

• Authors : Langlois J; Roche Pharma Research and Early Development, Neuroscience and Rare Diseases Discovery and Translational Area, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Grenzacherstrasse 124, 4070, Basel, Switzerland.; Lange S

Subjects: Microglia*/Microglia*/Microglia*/drug effects ; Microglia*/Microglia*/Microglia*/metabolism ; Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/Agammaglobulinaemia Tyrosine Kinase*/antagonists & inhibitors

• Source: Journal of neuroinflammation [J Neuroinflammation] 2024 Oct 27; Vol. 21 (1), pp. 276. Date of Electronic Publication: 2024 Oct 27.Publisher: BioMed Central Country of Publication: England NLM ID: 101222974 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-2094

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A Bruton tyrosine kinase inhibitor-resistance gene signature predicts prognosis and identifies TRIP13 as a potential therapeutic target in diffuse large B-cell lymphoma.

• Authors : Ding Y; Department of Hematology/Hematological Lab, The Second Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.; Huang K

Subjects: Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/genetics ; Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/Lymphoma, Large B-Cell, Diffuse*/drug therapy ; Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/Drug Resistance, Neoplasm*/genetics

• Source: Scientific reports [Sci Rep] 2024 Sep 11; Vol. 14 (1), pp. 21184. Date of Electronic Publication: 2024 Sep 11.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Cancer: Current Use and Future Prospects.

• Authors : Dickerson, Henry¹ (AUTHOR) ; Diab, Ahmad¹ (AUTHOR) ; Al Musaimi, Othman^1,2 (AUTHOR)

Subjects: *PROTEIN-tyrosine kinase inhibitors; *NON-small-cell lung carcinoma; *AFATINIB

• Source: International Journal of Molecular Sciences. Sep2024, Vol. 25 Issue 18, p10008. 22p.

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FMS-like Tyrosine Kinase 1 and Other Associated Factors to Predict in Vitro Fertilization (IVF) Outcomes in Different Causes of Infertility.

• Authors : Mohammed, Lubna S.¹; Haddad, Namir I. A.¹

Subjects: *MALE infertility; *PROTEIN-tyrosine kinases; *EMBRYO transfer

• Source: Iraqi Journal of Science. 2024, Vol. 65 Issue 8, p4179-4188. 10p.

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Combined targeting of GPX4 and BCR-ABL tyrosine kinase selectively compromises BCR-ABL+ leukemia stem cells.

• Authors : Zeng, Chengwu^1,2 (AUTHOR) ; Nie, Dingrui^2,3 (AUTHOR); Wang, Xianfeng² (AUTHOR)

• Source: Molecular Cancer. 10/28/2024, Vol. 23 Issue 1, p1-22. 22p.

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Protein Tyrosine Phosphatases : Structure, Signaling and Drug Discovery

• Authors : Lalima G. Ahuja

Subjects: Protein-tyrosine phosphataseSCIENCE / Chemistry / Clinical; SCIENCE / Life Sciences / Biochemistry; SCIENCE / Chemistry / General

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Phosphodiesterase inhibition and Gucy2C activation enhance tyrosine hydroxylase Ser40 phosphorylation and improve 6-hydroxydopamine-induced motor deficits.

• Authors : Douma, Erik H.^1,2 (AUTHOR); Stoop, Jesse¹ (AUTHOR); Lingl, Matthijs V. R.³ (AUTHOR)

• Source: Cell & Bioscience. 10/25/2024, Vol. 14 Issue 1, p1-23. 23p.

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Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition.

• Authors : Paramasivam, Prabu¹ (AUTHOR); Choi, Seong Won¹ (AUTHOR); Poddar, Ranjana¹ (AUTHOR)

• Source: Journal of Neuroinflammation. 10/22/2024, Vol. 21 Issue 1, p1-20. 20p.

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