نتائج البحث

Integrated mathematical and experimental modeling uncovers enhanced EMT plasticity upon loss of the DLC1 tumor suppressor.

• Authors : Höpfl, Sebastian^1,2 (AUTHOR); Özverin, Merih³ (AUTHOR); Nowack, Helena³ (AUTHOR)

• Source: PLoS Computational Biology. 5/12/2025, Vol. 21 Issue 5, p1-20. 20p.

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Integrated Analysis of Somatic DNA Variants and DNA Methylation of Tumor Suppressor Genes in Colorectal Cancer.

• Authors : Nishiki, Hisashi¹ (AUTHOR); Ura, Hiroki^2,3 (AUTHOR); Togi, Sumihito^2,3 (AUTHOR)

Subjects: *DNA analysis; *GENE expression; *DNA methylation

• Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 4, p1642. 22p.

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Tumor suppressor role of the complement inhibitor CSMD1 and its role in TNF-induced neuroinflammation in gliomas

• Authors : Tuysuz, Emre Can; Mourati, Eleni; Rosberg, Rebecca ...

Subjects: Medical and Health Sciences; Clinical Medicine; Cancer and Oncology

• Source: Journal of Experimental and Clinical Cancer Research. 43:1-16

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Molecular dynamics-based computational investigations on the influence of tumor suppressor p53 binding protein against other proteins/peptides.

• Authors : Abdalla M; Pediatric Research Institute, Children's Hospital Affiliated to Shandong University, Jinan, China. .; Abdelkhalig SM

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/chemistry ; Molecular Dynamics Simulation*

• Source: Scientific reports [Sci Rep] 2024 Dec 02; Vol. 14 (1), pp. 29871. Date of Electronic Publication: 2024 Dec 02.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Selective Up-Regulation of Tumor Suppressor Gene Retinoblastoma by Bisacridine Derivative Through Gene Promoter Quadruplex Structures for Cancer Treatment.

• Authors : Lin, Xiaomin¹ (AUTHOR); Zhang, Jiahui¹ (AUTHOR); Liang, Jihai¹ (AUTHOR)

Subjects: *SMALL molecules; *GENETIC regulation; *DRUG discovery

• Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 4, p1417. 26p.

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Antibacterial Activity of the p53 Tumor Suppressor Protein-How Strong Is the Evidence?

• Authors : Gdowicz-Kłosok A; Center for Translational Research and Molecular Biology of Cancer, Maria Skłodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-101 Gliwice, Poland.; Krześniak M

Subjects: Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/metabolism ; Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/Tumor Suppressor Protein p53*/genetics ; Anti-Bacterial Agents*/Anti-Bacterial Agents*/Anti-Bacterial Agents*/pharmacology

• Source: International journal of molecular sciences [Int J Mol Sci] 2025 May 06; Vol. 26 (9). Date of Electronic Publication: 2025 May 06.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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ALKBH4 functions as a hypoxia-responsive tumor suppressor and inhibits metastasis and tumorigenesis.

• Authors : Chen JL; Comprehensive Breast Health Center, Taipei Veterans General Hospital, Taipei, Taiwan.; Peng PH

Subjects: Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/pathology ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/genetics ; Carcinogenesis*/Carcinogenesis*/Carcinogenesis*/metabolism

• Source: Cellular oncology (Dordrecht, Netherlands) [Cell Oncol (Dordr)] 2025 Apr; Vol. 48 (2), pp. 425-435. Date of Electronic Publication: 2024 Oct 14.Publisher: Springer Country of Publication: Netherlands NLM ID: 101552938 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Uncovering a Novel Role of ROR1 in the Epigenetic Regulation of Tumor Suppressor Gene CREB3L1 in Triple-Negative Breast Cancer Cells.

• Authors : Reed VL; Department of Biology, St. Joseph's University, Philadelphia, PA 19131, USA.; Lalu E

Subjects: Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/genetics ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/metabolism ; Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/Triple Negative Breast Neoplasms*/pathology

• Source: Biomolecules [Biomolecules] 2025 May 16; Vol. 15 (5). Date of Electronic Publication: 2025 May 16.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X

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The X-Linked Tumor Suppressor TSPX Regulates Genes Involved in the EGFR Signaling Pathway and Cell Viability to Suppress Lung Adenocarcinoma.

• Authors : Kido, Tatsuo; Kong, Hui; Lau, Yun-Fai

Subjects: DENTT; EGFR signaling pathway; RNA-seq

• Source: Genes. 16(1)

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Characterization of RNA editing gene APOBEC3C as a candidate tumor suppressor in prostate cancer.

• Authors : Wang LY; Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences, Xi'an, 710119, China.; Shi J

Subjects: Cytidine Deaminase*/Cytidine Deaminase*/Cytidine Deaminase*/genetics ; Cytidine Deaminase*/Cytidine Deaminase*/Cytidine Deaminase*/metabolism ; RNA Editing*/RNA Editing*/RNA Editing*/genetics

• Source: Scientific reports [Sci Rep] 2025 May 22; Vol. 15 (1), pp. 17725. Date of Electronic Publication: 2025 May 22.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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