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Endogenous LRRK2 and PINK1 function in a convergent neuroprotective ciliogenesis pathway in the brain

• Authors : Bagnoli, Enrico; Lin, Yu-En; Burel, Sophie

Subjects: Animals; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/metabolism; Protein Kinases/metabolism

• Source: Bagnoli , E , Lin , Y-E , Burel , S , Jaimon , E , Antico , O , Themistokleous , C , Nikoloff , J M , Squires , S , Morella , I , Watzlawik , J O , Fiesel , F C , Springer , W , Tonelli , F , Lis , P

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The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes

• Authors : Füllbrunn, Nadia; Nicastro, Raffaele; Mari, Muriel

Subjects: GTPase-Activating Proteins; Endosomes; Vacuoles

• Source: Füllbrunn , N , Nicastro , R , Mari , M , Griffith , J , Herrmann , E , Rasche , R , Borchers , A-C , Auffarth , K , Kümmel , D , Reggiori , F , De Virgilio , C , Langemeyer , L & Ungermann , C 2024

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ER Membrane Contact Sites support endosomal small GTPase conversion for exosome secretion

• Authors : Verweij, Frederik; Bebelman, Maarten P; George, Anna ...

Subjects: Biological Transport; Cell Communication; Cell Membrane/metabolism

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A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation

• Authors : Vides, Edmundo G.; Adhikari, Ayan; Chiang, Claire Y.

Subjects: Leucine/metabolism; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics; Lipid Bilayers

• Source: Vides , E G , Adhikari , A , Chiang , C Y , Lis , P , Purlyte , E , Limouse , C , Shumate , J L , Spínola-Lasso , E , Dhekne , H S , Alessi , D R & Pfeffer , S R 2022 , ' A feed-forward pathway

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Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2.

• Authors : Singh, Ranjan K; Soliman, Ahmed; David, Joshua A

Subjects: info:eu-repo/classification/ddc/500; Adenosine Triphosphate: metabolism; Allosteric RegulationDE

• Source: Proceedings of the National Academy of Sciences of the United States of America 119(9), e2112712119 (2022). doi:10.1073/pnas.2112712119

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Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells

• Authors : Soelch, Susanne; Beaufort, Nathalie; Loessner, Daniela

Subjects: Female [MeSH]; Cell Line; Tumor [MeSH]

• Source: http://lobid.org/resources/99370697365106441#!, 27(1):158.

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Dysfunction of RAB39B-Mediated Vesicular Trafficking in Lewy Body Diseases.

• Authors : Koss, David J; Campesan, Susanna; Giorgini, Flaviano

Subjects: info:eu-repo/classification/ddc/610; Humans; Lewy Bodies: metabolismDE

• Source: Movement disorders 36(8), 1744 - 1758 (2021). doi:10.1002/mds.28605

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The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

• Authors : Reynier, Marie; Allart, Sophie; Goudounèche, Dominique ...

Subjects: MESH: Actin Cytoskeleton / metabolism; MESH: Actins / metabolism; MESH: Tight Junctions / metabolism

• Source: ISSN: 0022-202X.

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The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4.

• Authors : Funk, Natalja; Munz, Marita; Biskup, Saskia

Subjects: info:eu-repo/classification/ddc/600; Animals; Cell Survival: drug effectsDE

• Source: Scientific reports 9(1), 4515 (2019). doi:10.1038/s41598-019-40808-y

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Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

• Authors : Miserey-Lenkei, Stephanie; Bousquet, Hugo; Pylypenko, Olena ...

Subjects: Golgi; Membrane fission; Small GTPases

• Source: ISSN: 2041-1723.

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