نتائج البحث

PD-L1-Targeting Nanoparticles for the Treatment of Triple-Negative Breast Cancer: A Preclinical Model.

• Authors : Nevala, Wendy K.¹ (AUTHOR); Geng, Liyi^1,2 (AUTHOR); Xie, Hui^1,2 (AUTHOR)

• Source: International Journal of Molecular Sciences. Apr2025, Vol. 26 Issue 7, p3295. 18p.

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Time Course of Mitochondrial Antioxidant Markers in a Preclinical Model of Severe Penetrating Traumatic Brain Injury.

• Authors : Musyaju, Sudeep¹ (AUTHOR); Modi, Hiren R.¹ (AUTHOR); Shear, Deborah A.¹ (AUTHOR)

Subjects: *SPRAGUE Dawley rats; *BRAIN injuries; *OXIDATIVE stress

• Source: International Journal of Molecular Sciences. Feb2025, Vol. 26 Issue 3, p906. 24p.

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TET2 downregulation enhances the antitumor efficacy of CD19 CAR T cells in a preclinical model

• Authors : Yeongrin Kim; Moonjung Jeun; Heung Kyoung Lee

Subjects: CAR T cell; TET2; shRNA

• Source: Experimental Hematology & Oncology, Vol 14, Iss 1, Pp 1-4 (2025)

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Silymarin-Enriched Extract from Milk Thistle Activates Thermogenesis in a Preclinical Model of High-Fat-Diet-Induced Obesity to Relieve Systemic Meta-Inflammation.

• Authors : Reguero, Marina^1,2 ; Reglero, Guillermo³ ; Quintela, José Carlos²

Subjects: *IN vitro studies; *BODY temperature regulation; *ADIPOSE tissues

• Source: Nutrients. Dec2024, Vol. 16 Issue 23, p4166. 16p.

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Targeting PCSK9, through an innovative cVLP-based vaccine, enhanced the therapeutic activity of a cVLP-HER2 vaccine in a preclinical model of HER2-positive mammary carcinoma.

• Authors : Scalambra, Laura¹ (AUTHOR); Ruzzi, Francesca¹ (AUTHOR) ; Pittino, Olga Maria¹ (AUTHOR)

• Source: Journal of Translational Medicine. 1/30/2025, Vol. 23 Issue 1, p1-15. 15p.

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Acute and Subacute Oral Toxicity Assessment of The Polysaccharides Extracted from Clinacanthus nutans Leaves: A Preclinical Model for Drug Safety Screening.

• Authors : Tan Yong Chia^1,2 ; Chee-Yuen Gan¹ ; Kaur, Gurjeet³

• Source: Tropical Life Sciences Research. 2025, Vol. 36 Issue 1, p245-276. 32p.

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Distinct gut microbial signature and altered short chain fatty acid metabolism at disease onset in a rat preclinical model of superimposed preeclampsia.

• Authors : Alhasan, Moumen M.¹ (AUTHOR); Landa, María S.^2,3 (AUTHOR); García, Silvia I.^2,3,4 (AUTHOR)

• Source: Scientific Reports. 12/30/2024, Vol. 14 Issue 1, p1-12. 12p.

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Inactivity‐mediated molecular adaptations: Insights from a preclinical model of physical activity reduction.

• Authors : Meyer, Alice¹ (AUTHOR); Kim, Nicole² (AUTHOR); Nguyen, Melissa³ (AUTHOR)

• Source: Physiological Reports. Dec2024, Vol. 12 Issue 23, p1-16. 16p.

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Validation of a Preclinical Model Based on Patient-derived Organoids for the Study of the Gut-joint Axis in Spondyloarthritis (ORGANOSPA)

• Source: Validation of a Preclinical Model Based on Patient-derived Organoids for the Study of the Gut-joint Axis in Spondyloarthritis

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Patient-derived xenografts from circulating cancer stem cells as a preclinical model for personalized pancreatic cancer research

• Authors : Benedikt J. Wagner; Andreas Ettner-Sitter; Nicolas A. Ihlo

Subjects: Pancreatic cancer; Cancer stem cell; Chorioallantoic membrane

• Source: Scientific Reports, Vol 15, Iss 1, Pp 1-13 (2025)

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