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Cellular Distribution and Ultrastructural Changes in HaCaT Cells, Induced by Podophyllotoxin and Its Novel Fluorescent Derivative, Supported by the Molecular Docking Studies.

• Authors : Strus, Piotr¹ (AUTHOR) ; Sadowski, Karol² (AUTHOR) ; Kostro, Julia² (AUTHOR)

Subjects: *MOLECULAR docking; *TUBULINS; *PODOPHYLLOTOXIN

• Source: International Journal of Molecular Sciences. Jun2024, Vol. 25 Issue 11, p5948. 20p.

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Podophyllic Aldehyde, a Podophyllotoxin Derivate, Elicits Different Cell Cycle Profiles Depending on the Tumor Cell Line: A Systematic Proteomic Analysis.

• Authors : Hernández, Ángela-Patricia^1,2 (AUTHOR) ; Chaparro-González, Lorea¹ (AUTHOR) ; Garzo-Sánchez, Olga¹ (AUTHOR)

Subjects: *CELL cycle; *PODOPHYLLOTOXIN; *ALDEHYDES

• Source: International Journal of Molecular Sciences. May2024, Vol. 25 Issue 9, p4631. 17p.

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Design, synthesis and biological evaluation of novel podophyllotoxin derivatives as tubulin-targeting anticancer agents.

• Authors : Guo Y; Institute of Clinical Pharmacy, Jining First People's Hospital, Shandong First Medical University, Jining, P.R. China.; Translational Pharmaceutical Laboratory, Jining First People's Hospital, Shandong First Medical University, Jining, P.R. China.

Subjects: Podophyllotoxin*/Podophyllotoxin*/Podophyllotoxin*/pharmacology ; Podophyllotoxin*/Podophyllotoxin*/Podophyllotoxin*/chemistry ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/pharmacology

• Source: Pharmaceutical biology [Pharm Biol] 2024 Dec; Vol. 62 (1), pp. 233-249. Date of Electronic Publication: 2024 Feb 23.Publisher: Taylor & Francis Country of Publication: England NLM ID: 9812552 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Genomic characterization and identification of candidate genes for putative podophyllotoxin biosynthesis pathway in Penicillium herquei HGN12.1C.

• Authors : Nguyen DH; Institute of Biotechnology (IBT), Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.; Tran QH

Subjects: Podophyllotoxin*/Podophyllotoxin*/Podophyllotoxin*/biosynthesis ; Podophyllotoxin*/Podophyllotoxin*/Podophyllotoxin*/analogs & derivatives ; Penicillium*/Penicillium*/Penicillium*/genetics

• Source: Microbial biotechnology [Microb Biotechnol] 2024 Sep; Vol. 17 (9), pp. e70007.Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 101316335 Publication Model: Print Cited Medium: Internet ISSN:

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Anthriscus sylvestris Deoxypodophyllotoxin Synthase Involved in the Podophyllotoxin Biosynthesis.

• Authors : Kobayashi, Keisuke¹ (AUTHOR); Yamamura, Masaomi^1,2 (AUTHOR); Mikami, Bunzo¹ (AUTHOR)

Subjects: *DIOXYGENASES; *CYTOCHROME P-450; *PODOPHYLLOTOXIN

• Source: Plant & Cell Physiology. Dec2023, Vol. 64 Issue 12, p1436-1448. 13p.

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Podophyllotoxin and Aryltetralin Lignans: Methods for the Synthesis of Rings A, B, C, D

• Authors : Francisco Flores-Hernández; Tania Isabel Zárate-López; Marco Antonio Alcaráz-Cano

Subjects: lignans; podophyllotoxin; aryltetralin-lignans

• Source: Журнал органічної та фармацевтичної хімії, Vol 22, Iss 2, Pp 3-25 (2024)

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PROTAC EZH2 degrader-1 overcomes the resistance of podophyllotoxin derivatives in refractory small cell lung cancer with leptomeningeal metastasis.

• Authors : Shi MX; Department of Respiratory and Critical Care Medicine, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, 200092, Shanghai, China.; Ding X

Subjects: Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/drug therapy ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/pathology ; Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/Small Cell Lung Carcinoma*/metabolism

• Source: BMC cancer [BMC Cancer] 2024 Apr 22; Vol. 24 (1), pp. 504. Date of Electronic Publication: 2024 Apr 22.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Podophyllotoxin: Recent Advances in the Development of Hybridization Strategies to Enhance Its Antitumoral Profile.

• Authors : Miranda-Vera, Carolina¹ (AUTHOR) ; Hernández, Ángela Patricia¹ (AUTHOR) ; García-García, Pilar¹ (AUTHOR)

• Source: Pharmaceutics. Dec2023, Vol. 15 Issue 12, p2728. 58p.

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L-Cysteine-Modified Transfersomes for Enhanced Epidermal Delivery of Podophyllotoxin.

• Authors : Niu, Jiangxiu¹ (AUTHOR); Yuan, Ming¹ (AUTHOR); Chen, Jingjing¹ (AUTHOR)

Subjects: *SKIN permeability; *ZETA potential; *PROPER orthogonal decomposition

• Source: Molecules. Aug2023, Vol. 28 Issue 15, p5712. 19p.

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A natural compound-empowered podophyllotoxin prodrug nanoassembly magnifies efficacy-toxicity benefits in cancer chemotherapy.

• Authors : Ziqi Lin¹; Yuequan Wang¹; Wenwen Li¹

• Source: Asian Journal of Pharmaceutical Sciences. Aug2024, Vol. 19 Issue 4, p1-12. 12p.

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