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A Study of Panobinostat in Pediatric Patients With Solid Tumors Including MRT/ATRT (NORTH)

• Authors : National Health and Medical Research Council, Australia; Secura Bio, Inc.

• Source: A Phase II Study of Panobinostat in Pediatric, Adolescent and Young Adult Patients With Solid Tumors Including Osteosarcoma, Malignant Rhabdoid Tumor/Atypical Teratoid

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Drug prioritization identifies panobinostat as a tailored treatment element for patients with metastatic hepatoblastoma.

• Authors : Demir S; Department of Pediatric Surgery, Dr. von Hauner Children's Hospital, University Hospital, LMU Munich, Lindwurmstreet 2a, Munich, 80337, Germany.; Hotes A

Subjects: Panobinostat*/Panobinostat*/Panobinostat*/pharmacology ; Panobinostat*/Panobinostat*/Panobinostat*/therapeutic use ; Hepatoblastoma*/Hepatoblastoma*/Hepatoblastoma*/drug therapy

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2024 Nov 12; Vol. 43 (1), pp. 299. Date of Electronic Publication: 2024 Nov 12.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Panobinostat Attenuates Experimental Autoimmune Encephalomyelitis in Mice via Suppressing Oxidative Stress-Related Neuroinflammation and Mitochondrial Dysfunction.

• Authors : Shen Y; Beijing Key Laboratory of Drug Targets Identification and Drug Screening, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.; Zhao J

Subjects: Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/drug therapy ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/metabolism ; Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/Encephalomyelitis, Autoimmune, Experimental*/pathology

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 09; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Anti-tumour activity of Panobinostat in oesophageal adenocarcinoma and squamous cell carcinoma cell lines.

• Authors : Lopes N; Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP) - (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC), Research Center-LAB 3, F Bdg, 1st Floor, Rua Dr. António Bernardino de Almeida, 4200-072, Porto, Portugal.; Salta S

Subjects: Panobinostat*/Panobinostat*/Panobinostat*/pharmacology ; Panobinostat*/Panobinostat*/Panobinostat*/therapeutic use ; Panobinostat*/Panobinostat*/Panobinostat*/administration & dosage Adenocarcinoma Of Esophagus

• Source: Clinical epigenetics [Clin Epigenetics] 2024 Aug 03; Vol. 16 (1), pp. 102. Date of Electronic Publication: 2024 Aug 03.Publisher: Biomed Central Country of Publication: Germany NLM ID: 101516977 Publication Model: Electronic Cited Medium: Internet ISSN: 1868-7083

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Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple Myeloma

• Authors : National Cancer Institute (NCI)

• Source: Panobinostat Combined With High-Dose Gemcitabine/Busulfan/Melphalan With Autologous Stem Cell Transplant for Patients With Refractory/Relapsed Myeloma

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Panobinostat in Combination With Daratumumab, Bortezomib and Dexamethasone for the Treatment of Relapsed/Refractory Multiple Myeloma

• Authors : Abdullah Khan, Principal Investigator

• Source: A Phase I Study of Panobinostat in Combination With Daratumumab, Bortezomib, and Dexamethasone in Patients With Relapsed/Refractory Multiple Myeloma

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Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma (PBTC-047)

• Authors : National Cancer Institute (NCI)

• Source: Phase 1 Trial of Panobinostat in Children With Diffuse Intrinsic Pontine Glioma

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Phase I Study of Marizomib + Panobinostat for Children With DIPG (DIPG)

• Authors : Celgene; Secura Bio, Inc.; Katherine Warren, MD, Principal Investigator

• Source: Phase 1 Trial of Marizomib Alone and in Combination With Panobinostat for Children With Diffuse Intrinsic Pontine Glioma

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Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease (LBH589)

• Authors : Secura Bio, Inc.; Abdullah Kutlar, Professor of Medicine, Director of Augusta University Sickle Cell Center

• Source: Phase I Study to Determine the Safety and Tolerability of Escalating Doses of Panobinostat (LBH589) in Patients With Sickle Cell Disease

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Panobinostat and Ruxolitinib In MyElofibrosis (PRIME Trial) (PRIME)

• Authors : John Mascarenhas, Associate Professor of Medicine, Hematology and Medical Oncology

• Source: Panobinostat and Ruxolitinib In MyElofibrosis (PRIME STUDY) - Phase I/II Study of Combination Oral JAK2 Tyrosine Kinase Inhibitor (JAK2-TKI) and Histone Deacetylase

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