نتائج البحث

Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.

• Authors : Uda M; School of Nursing, Hirosaki Gakuin University, Hirosaki, Aomori, Japan.; Yoshihara T

Subjects: Mevalonic Acid*/Mevalonic Acid*/Mevalonic Acid*/metabolism ; Mevalonic Acid*/Mevalonic Acid*/Mevalonic Acid*/pharmacology ; Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/Proto-Oncogene Proteins c-akt*/metabolism

• Source: Physiological reports [Physiol Rep] 2024 Mar; Vol. 12 (5), pp. e15969.Publisher: published by Wiley Periodicals, Inc. on behalf of the American Physiological Society and The Physiological Society Country of Publication: United States NLM

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EYA3 promotes the tumorigenesis of gastric cancer through activation of the mTORC1 signaling pathway and inhibition of autophagy.

• Authors : Xu Z; Department of Oncology, Nantong Haimen People's Hospital, Nantong, 226199, China.; Liu J

Subjects: Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/pathology ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/genetics ; Stomach Neoplasms*/Stomach Neoplasms*/Stomach Neoplasms*/metabolism

• Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28355. Date of Electronic Publication: 2024 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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The Combined Inhibition of SREBP and mTORC1 Signaling Synergistically Inhibits B-Cell Lymphoma.

• Authors : Zhu Z; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, Indiana, USA.; Jiang W

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/antagonists & inhibitors ; Signal Transduction*/Signal Transduction*/Signal Transduction*/drug effects

• Source: Cancer medicine [Cancer Med] 2024 Nov; Vol. 13 (21), pp. e70342.Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN:

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Effects of hindlimb unloading on the mevalonate and mechanistic target of rapamycin complex 1 signaling pathways in a fast-twitch muscle in rats.

• Authors : Munehiro Uda¹ ; Toshinori Yoshihara²; Noriko Ichinoseki-Sekine^2,3

• Source: Physiological Reports. Mar2024, Vol. 12 Issue 5, p1-15. 15p.

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A Novel 14mer Peptide Inhibits Autophagic Flux via Selective Activation of the mTORC1 Signalling Pathway: Implications for Alzheimer's Disease.

• Authors : García Porta C; Neuro-Bio Ltd., Building F5, Culham Science Centre, Abingdon OX14 3DB, UK.; Mahfooz K

Subjects: Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/metabolism ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/pathology ; Alzheimer Disease*/Alzheimer Disease*/Alzheimer Disease*/drug therapy

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 29; Vol. 25 (23). Date of Electronic Publication: 2024 Nov 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Starvation-induced metabolic rewiring affects mTORC1 composition in vivo.

• Authors : Edgar K; Institute for Biochemistry and Molecular Biology, Medical Faculty, Rheinische Friedrich-Wilhelms-University of Bonn, 53115, Bonn, Germany.; Simone M

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Lysosomes*/Lysosomes*/Lysosomes*/metabolism ; Starvation*/Starvation*/Starvation*/metabolism

• Source: Scientific reports [Sci Rep] 2024 Nov 16; Vol. 14 (1), pp. 28296. Date of Electronic Publication: 2024 Nov 16.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Nuclear mTORC1 Live-Cell Sensor nTORSEL Reports Differential Nuclear mTORC1 Activity in Cell Lines.

• Authors : Wang Y; School of Medicine, Shenzhen Campus of Sun Yat-Sen University, Sun Yat-Sen University, Shenzhen 518107, China.; Li C

Subjects: Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/Mechanistic Target of Rapamycin Complex 1*/metabolism ; Cell Nucleus*/Cell Nucleus*/Cell Nucleus*/metabolism; Humans

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 12; Vol. 25 (22). Date of Electronic Publication: 2024 Nov 12.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Bifidobacterium pseudolongum-Derived Bile Acid from Dietary Carvacrol and Thymol Supplementation Attenuates Colitis via cGMP-PKG-mTORC1 Pathway.

• Authors : Zhang K; College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China.; Xu Y

Subjects: Colitis*/Colitis*/Colitis*/metabolism ; Colitis*/Colitis*/Colitis*/drug therapy ; Bile Acids and Salts*/Bile Acids and Salts*/Bile Acids and Salts*/metabolism

• Source: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Nov; Vol. 11 (43), pp. e2406917. Date of Electronic Publication: 2024 Sep 23.Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844

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Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes, via activation of mTORC1 in the medial prefrontal cortex in lipopolysaccharide-induced depression model mice.

• Authors : Deyama S; Laboratory of Molecular Pharmacology, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.; Sugie R

Subjects: Tomatine*/Tomatine*/Tomatine*/analogs & derivatives ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/pharmacology ; Antidepressive Agents*/Antidepressive Agents*/Antidepressive Agents*/administration & dosage

• Source: Nutritional neuroscience [Nutr Neurosci] 2024 Aug; Vol. 27 (8), pp. 795-808. Date of Electronic Publication: 2023 Sep 13.Publisher: Taylor & Francis Country of Publication: England NLM ID: 100892202 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction.

• Authors : Huang KC; Department of Biology, Indiana University Purdue University Indianapolis, Indianapolis, IN, USA.; Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, USA.

Subjects: Retinal Ganglion Cells*/Retinal Ganglion Cells*/Retinal Ganglion Cells*/pathology ; Retinal Ganglion Cells*/Retinal Ganglion Cells*/Retinal Ganglion Cells*/metabolism ; Autophagy*/Autophagy*/Autophagy*/physiology

• Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 Oct 18; Vol. 12 (1), pp. 164. Date of Electronic Publication: 2024 Oct 18.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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