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Exploring the Feasibility of a Bracketing Approach Utilizing Modeling for Development of Long-Acting Injectables for Regulatory Approval—A Case Study Using Levonorgestrel.

• Authors : Cole, Susan¹ (AUTHOR); Pertinez, Henry² (AUTHOR); Butler, Andrew S.¹ (AUTHOR)

• Source: Pharmaceuticals (14248247). Dec2024, Vol. 17 Issue 12, p1640. 19p.

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The suture fixation of the levonorgestrel-releasing intrauterine device with hysteroscope for the treatment of adenomyosis in patients at high risk of device expulsion-a prospective observational study.

• Authors : Mao, Min¹ (AUTHOR); Gou, Yuanqin¹ (AUTHOR); Luo, Zhigui² (AUTHOR)

• Source: BMC Women's Health. 10/9/2024, Vol. 24 Issue 1, p1-6. 6p.

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Hormone-related side effects in new users of a levonorgestrel 52-mg intrauterine device

• Authors : Kerns, Jennifer L; Keder, Lisa M; Cwiak, Carrie A

Subjects: Reproductive Medicine; Biomedical and Clinical Sciences; Infectious Diseases

• Source: American Journal of Obstetrics and Gynecology. 231(6)

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Levonorgestrel-Releasing Intrauterine System With or Without Everolimus in Treating Patients With Atypical Hyperplasia or Stage IA Grade 1 Endometrial Cancer (LEVER)

• Authors : National Cancer Institute (NCI)

• Source: Phase II Study of the Levonorgestrel Intrauterine Device Alone or in Combination With the mTORC1 Inhibitor, Everolimus, for the Treatment of Complex Atypical Hyperplasia

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Levonorgestrel-Releasing Intrauterine System in Treating Patients With Complex Atypical Hyperplasia or Grade I Endometrial Cancer

• Authors : National Cancer Institute (NCI)

• Source: A Phase II Study of the Levonorgestrel Intrauterine Device (Mirena) to Treat Complex Atypical Hyperplasia and Grade 1 Endometrioid Endometrial CarcinomaWestin SN,

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A Study in Healthy Participants to Evaluate the Effects of Multiple Doses of JNJ-55308942 on Cytochrome P450 Substrate Activity and on the Pharmacokinetics of Levonorgestrel/Ethinyl Estradiol

• Source: An Open-Label Drug Interaction Study in Healthy Subjects to Evaluate the Effects of Multiple Doses of JNJ55308942 on the Cytochrome P450 CYP3A4, CYP2D6 and CYP2C19 Activity and on the Pharmacokinetics

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A Study to Evaluate the Effect of Multiple Oral Doses of JNJ-42847922 on the Steady-state Pharmacokinetics of an Oral Contraceptive Containing Ethinyl Estradiol and Levonorgestrel in Healthy Female Adult Participants

• Source: An Open-label Drug-drug Interaction Study in Healthy Female Adult Subjects to Investigate the Effect of Multiple Oral Doses of JNJ-42847922 on the Steady-state Pharmacokinetics of an Oral

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Levonorgestrel at emergency contraception dose has no effect on ciliary beat frequency and muscular contraction of the human fallopian tube: an in vitro experimental study.

• Authors : Li RHW; Department of Obstetrics and Gynaecology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 102 Pokfulam Road, Pok Fu Lam, Hong Kong. .; Liao SB

Subjects: Levonorgestrel*/Levonorgestrel*/Levonorgestrel*/pharmacology ; Levonorgestrel*/Levonorgestrel*/Levonorgestrel*/administration & dosage ; Fallopian Tubes*/Fallopian Tubes*/Fallopian Tubes*/drug effects

• Source: Reproductive biology and endocrinology : RB&E [Reprod Biol Endocrinol] 2024 Nov 19; Vol. 22 (1), pp. 147. Date of Electronic Publication: 2024 Nov 19.Publisher: BioMed Central Country of Publication: England NLM ID: 101153627 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-7827

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The efficacy of the levonorgestrel intrauterine system versus oral megestrol acetate in treating atypical endometrial hyperplasia: a superior randomized controlled trial.

• Authors : Alnemr, Amr A.¹; Harb, Ola A.²; Atia, Hytham¹

• Source: Journal of Gynecologic Oncology. Sep2024, Vol. 35 Issue 5, p1-12. 12p.

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Levonorgestrel-piroxicam Versus Ulipristal Acetate for Emergency Contraception

• Authors : The Family Planning Association of Hong Kong

• Source: Levonorgestrel-piroxicam Combination Versus Ulipristal Acetate for Emergency Contraception: a Randomised Double-blind Controlled Trial

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