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Integrins in Health and Disease—Suitable Targets for Treatment?

• Authors : Klaus, Tanja¹ (AUTHOR) ; Hieber, Christoph¹ (AUTHOR); Bros, Matthias¹ (AUTHOR)

• Source: Cells (2073-4409). Feb2024, Vol. 13 Issue 3, p212. 35p.

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Overcoming Vemurafenib Resistance in Metastatic Melanoma: Targeting Integrins to Improve Treatment Efficacy.

• Authors : Boz Er, Asiye Busra¹ (AUTHOR) ; Sheldrake, Helen M.¹ (AUTHOR) ; Sutherland, Mark² (AUTHOR)

Subjects: *VEMURAFENIB; *BRAF genes; *INTEGRINS

• Source: International Journal of Molecular Sciences. Jul2024, Vol. 25 Issue 14, p7946. 23p.

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β1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter.

• Authors : Halder, Sebok K.¹ (AUTHOR); Sapkota, Arjun¹ (AUTHOR); Milner, Richard¹ (AUTHOR)

• Source: Acta Neuropathologica Communications. 3/20/2024, Vol. 12 Issue 1, p1-13. 13p.

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Laminin-associated integrins mediate Diffuse Intrinsic Pontine Glioma infiltration and therapy response within a neural assembloid model.

• Authors : Sinha S; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.; Huang MS

Subjects: Laminin*/Laminin*/Laminin*/metabolism ; Integrins*/Integrins*/Integrins*/metabolism ; Brain Stem Neoplasms*/Brain Stem Neoplasms*/Brain Stem Neoplasms*/genetics

• Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2024 May 05; Vol. 12 (1), pp. 71. Date of Electronic Publication: 2024 May 05.Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960

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Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand.

• Authors : Takada, Yoshikazu^1,2 (AUTHOR) ; Fujita, Masaaki¹ (AUTHOR) ; Takada, Yoko K.¹ (AUTHOR)

• Source: Cells (2073-4409). Sep2023, Vol. 12 Issue 18, p2265. 16p.

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A computational analysis of the role of integrins and Rho-GTPases in the emergence and disruption of apical-basal polarization in renal epithelial cells.

• Authors : Hagelaars MJ; Eindhoven University of Technology, Department of Biomedical Engineering, Eindhoven, The Netherlands.; Institute for Complex Molecular Systems, Eindhoven, The Netherlands.

Subjects: Cell Polarity*/Cell Polarity*/Cell Polarity*/physiology ; Integrins*/Integrins*/Integrins*/metabolism ; Epithelial Cells*/Epithelial Cells*/Epithelial Cells*/metabolism

• Source: PLoS computational biology [PLoS Comput Biol] 2024 May 20; Vol. 20 (5), pp. e1012140. Date of Electronic Publication: 2024 May 20 (Print Publication: 2024).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Integrins as the pivotal regulators of cisplatin response in tumor cells.

• Authors : Nasimi Shad A; Student Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.; Moghbeli M

Subjects: Cisplatin*/Cisplatin*/Cisplatin*/pharmacology ; Cisplatin*/Cisplatin*/Cisplatin*/therapeutic use ; Integrins*/Integrins*/Integrins*/metabolism

• Source: Cell communication and signaling : CCS [Cell Commun Signal] 2024 May 13; Vol. 22 (1), pp. 265. Date of Electronic Publication: 2024 May 13.Publisher: BioMed Central Country of Publication: England NLM ID: 101170464 Publication Model: Electronic Cited Medium: Internet ISSN: 1478-811X

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Modulation of αv integrins by lebecetin, a viper venom-derived molecule, in experimental neuroinflammation and demyelination models

• Authors : Nour-elhouda Neili; Zaineb AbdelKafi-Koubaa; Jed Jebali

Subjects: Neuroinflammation; Demyelination; Integrins

• Source: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

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225 Ac-iPSMA-RGD for Alpha-Therapy Dual Targeting of Stromal/Tumor Cell PSMA and Integrins.

• Authors : Ocampo-García, Blanca¹ (AUTHOR) ; Cruz-Nova, Pedro¹ (AUTHOR) ; Jiménez-Mancilla, Nallely² (AUTHOR)

Subjects: *INTEGRINS; *DOUBLE-strand DNA breaks; *CANCER cells

• Source: International Journal of Molecular Sciences. Dec2023, Vol. 24 Issue 23, p16553. 21p.

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Virtual Screening of Protein Data Bank via Docking Simulation Identified the Role of Integrins in Growth Factor Signaling, the Allosteric Activation of Integrins, and P-Selectin as a New Integrin Ligand.

• Authors : Fujita, Masaaki; Takada, Yoko; Takada, Yoshikazu

Subjects: growth factor signaling; integrins; receptors

• Source: Cells. 12(18)

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