نتائج البحث

Stretching the structural envelope of imatinib to reduce β-amyloid production by modulating both β- and γ-secretase cleavages of APP.

• Authors : Netzer, William J.¹ ; Sinha, Anjana¹ ; Ghias, Mondana¹

• Source: Frontiers in Chemistry. 2024, p1-40. 40p.

تفاصيل العنوان

پیشگویی تمایل اتصال تعدادی از مشتقات ایماتینیب به عنوان مهار کننده های تیروزین کیناز بر اساس بهینه سازی مونت کارلو.

• Authors : شهرام لطفی¹; شهین احمدی² ; شراره وردست باغم³

Subjects: *THERAPEUTIC use of antineoplastic agents; *STATISTICAL correlation; *HEMATOLOGIC malignanciesIRAN

• Source: Journal of Ilam University of Medical Sciences. 2024, Vol. 32 Issue 4, p66-86. 21p.

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Assessment of Imatinib Anti-Remodeling Activity on a Human Precision Cut Lung Slices Model.

• Authors : Bozzini, Sara¹ (AUTHOR) ; Bozza, Eleonora² (AUTHOR); Bagnera, Cecilia² (AUTHOR)

Subjects: *PROTEIN-tyrosine kinase inhibitors; *PULMONARY fibrosis; *EPITHELIAL cells

• Source: International Journal of Molecular Sciences. Aug2024, Vol. 25 Issue 15, p8186. 12p.

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Discontinuation of imatinib in patients with oligometastatic gastrointestinal stromal tumour who are in complete radiological remission: a prospective multicentre phase II study

• Authors : Hompland, I; Boye, K; Wiedswang, AM

Subjects: Medicin och hälsovetenskap

• Source: Acta oncologica (Stockholm, Sweden). 63:288-293

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Study to Allow Access to Imatinib for Patients Who Are on Imatinib Treatment in a Novartis-sponsored Study and Are Benefiting From the Treatment as Judged by the Investigator

• Source: An Open Label, Multi-center Imatinib Roll-over Protocol for Patients Who Have Completed a Previous Novartis-sponsored Imatinib Study and

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Vitamin K2 Protects Against SARS-CoV-2 Envelope Protein-Induced Cytotoxicity in Chronic Myeloid Leukemia Cells and Enhances Imatinib Activity.

• Authors : Okabe S; Department of Hematology, Tokyo Medical University, Tokyo 160-0023, Japan.; Arai Y

Subjects: Imatinib Mesylate*/Imatinib Mesylate*/Imatinib Mesylate*/pharmacology ; Imatinib Mesylate*/Imatinib Mesylate*/Imatinib Mesylate*/therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/Leukemia, Myelogenous, Chronic, BCR-ABL Positive*/drug therapy

• Source: International journal of molecular sciences [Int J Mol Sci] 2024 Nov 02; Vol. 25 (21). Date of Electronic Publication: 2024 Nov 02.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Impact of systemic steroids on the efficacy of first line imatinib treatment of patients with advanced gastrointestinal stromal tumors (GISTs).

• Authors : Kim S; Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.; Kim HD

Subjects: Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/drug therapy ; Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/mortality ; Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/Gastrointestinal Stromal Tumors*/pathology

• Source: BMC cancer [BMC Cancer] 2024 Oct 08; Vol. 24 (1), pp. 1245. Date of Electronic Publication: 2024 Oct 08.Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407

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Imatinib‑ and ponatinib‑mediated cardiotoxicity in zebrafish embryos and H9c2 cardiomyoblasts.

• Authors : Zakaria ZZ; Vice President of Health and Medical Sciences Office, QU Health, Qatar University, Doha 2713, Qatar.; Suleiman M

Subjects: Zebrafish*/Zebrafish*/Zebrafish*/embryology ; Imidazoles*/Imidazoles*/Imidazoles*/toxicity ; Pyridazines*/Pyridazines*/Pyridazines*/adverse effects

• Source: Molecular medicine reports [Mol Med Rep] 2024 Oct; Vol. 30 (4). Date of Electronic Publication: 2024 Sep 02.Publisher: D. A. Spandidos Country of Publication: Greece NLM ID: 101475259 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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High Level of CD8 + PD-1 + Cells in Patients with Chronic Myeloid Leukemia Who Experienced Loss of MMR after Imatinib Discontinuation.

• Authors : Kwaśnik, Paulina¹ (AUTHOR) ; Zaleska, Joanna¹ (AUTHOR); Link-Lenczowska, Dorota² (AUTHOR)

• Source: Cells (2073-4409). Apr2024, Vol. 13 Issue 8, p723. 15p.

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METHOD DEVELOPMENT AND VALIDATION FOR QUANTIFICATION OF IMATINIB MESYLATE SPIKED IN VITRO SALIVA BY LC-MS/MS.

• Authors : Remidicherla, Swetha Sri^1,2; Chakravarthi, Guntupalli² ; S., Pravallika²

• Source: Indian Drugs. Apr2024, Vol. 61 Issue 4, p46-56. 11p.

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