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Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

• Authors : Zhaoyuan Xue; Yiliyaer Nuerrula; Yilidana Sitiwaerdi

Subjects: Nuclear factor erythroid 2-related factor 2 (NRF2); glutamate-cysteine ligase modifier subunit (GCLM); radioresistance

• Source: Biomolecules & Biomedicine (2024)

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Glutamate-Cysteine Ligase Variant and Method of Producing Glutathione Using the Same

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Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

• Authors : Xue, Zhaoyuan; Nuerrula, Yiliyaer; Sitiwaerdi, Yilidana

Subjects: Nuclear factor erythroid 2-related factor 2 (NRF2); glutamate-cysteine ligase modifier subunit (GCLM); radioresistance

• Source: Biomolecules and Biomedicine; Vol. 24 No. 3 (2024); 545–559 ; 2831-090X ; 2831-0896

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SNORA56-mediated pseudouridylation of 28 S rRNA inhibits ferroptosis and promotes colorectal cancer proliferation by enhancing GCLC translation.

• Authors : Xu C; Department of Laboratory Medicine, Shanghai Tenth People's Hospital of Tongji University, Shanghai, 200072, China.; Bian Z

Subjects: Colorectal Neoplasms*/Colorectal Neoplasms*/Colorectal Neoplasms*/genetics ; Ferroptosis*/Ferroptosis*/Ferroptosis*/genetics ; Glutamate-Cysteine Ligase*

• Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Dec 05; Vol. 42 (1), pp. 331. Date of Electronic Publication: 2023 Dec 05.Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966

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Uric acid effects on glutathione metabolism estimated by induction of glutamate-cysteine ligase, glutathione reductase and glutathione synthetase in mouse J744A.1 macrophage cell line

• Authors : Deyana Vankova; Yoana Kiselova-Kaneva; Diana Ivanova

Subjects: Medicine

• Source: Folia Medica, Vol 64, Iss 5, Pp 762-769 (2022)

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Glutamate Cysteine Ligase Modifier Subunit (Gclm) Null Mice Have Increased Ovarian Oxidative Stress and Accelerated Age-Related Ovarian Failure

• Authors : Lim, Jinhwan; Nakamura, Brooke N; Mohar, Isaac

Subjects: Ovarian Cancer; Infertility; Cancer

• Source: Endocrinology. 156(9)

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The Impact of Genetic Polymorphisms in Glutamate-Cysteine Ligase, a Key Enzyme of Glutathione Biosynthesis, on Ischemic Stroke Risk and Brain Infarct Size.

• Authors : Polonikov, Alexey^1,2 (AUTHOR) ; Bocharova, Iuliia^3,4 (AUTHOR); Azarova, Iuliia^5,6 (AUTHOR)

• Source: Life (2075-1729). Apr2022, Vol. 12 Issue 4, pN.PAG-N.PAG. 35p.

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Covalent Targeting of Glutamate Cysteine Ligase to Inhibit Glutathione Synthesis

• Authors : Zhang, Lydia Hanping

Subjects: Biology; Chemistry; Pharmaceutical sciences

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Exercise induced upregulation of glutamate-cysteine ligase catalytic subunit and glutamate-cysteine ligase modifier subunit gene expression in Thoroughbred horses

• Authors : Jeong-Woong Park; Jae-Young Choi; Seul A Hong

Subjects: Horse; Exercise; Glutamate-cysteine Ligase Catalytic Subunit ()

• Source: Asian-Australasian Journal of Animal Sciences, Vol 30, Iss 5, Pp 728-735 (2017)

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Increased Sensitivity to Testicular Toxicity of Transplacental Benzo[a]pyrene Exposure in Male Glutamate Cysteine Ligase Modifier Subunit Knockout (Gclm−/−) Mice

• Authors : Nakamura, Brooke N; Mohar, Isaac; Lawson, Gregory W

Subjects: Infertility; Prevention; Contraception/Reproduction

• Source: Toxicological Sciences. 126(1)

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