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Model-Informed Drug Development of a Sustained Release Formulation of Flucytosine in the Treatment of Cryptococcal Meningitis: A Case Study Using Physiologically Based Pharmacokinetic Modeling.

• Authors : Eriksson J; Pharmetheus, Uppsala, Sweden.; Sjögren E

Subjects: Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/pharmacokinetics ; Antifungal Agents*/Antifungal Agents*/Antifungal Agents*/administration & dosage ; Drug Development*/Drug Development*/Drug Development*/methods

• Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2025 Apr; Vol. 14 (4), pp. 651-657. Date of Electronic Publication: 2025 Feb 25.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST) (LAmB-FAST)

• Authors : National Institute of Allergy and Infectious Diseases (NIAID); Pham Ngoc Thach University of Medicine; Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

• Source: Liposomal Amphotericin B and Flucytosine Antifungal Strategy for Talaromycosis (LAmB-FAST)

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Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

• Source: Optimizing the Dose of Flucytosine for the Treatment of Cryptococcal Meningitis

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Rapid in vitro evolution of flucytosine resistance in Candida auris

• Authors : Trinh Phan-Canh; Duc-Minh Nguyen-Le; Phuc-Loi Luu

Subjects: Candida auris; flucytosine; 5FC

• Source: mSphere, Vol 10, Iss 4 (2025)

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Bioavailability of three novel oral, sustained-release pellets, relative to an immediate-release tablet containing 500 mg flucytosine: A randomized, open-label, crossover study in healthy volunteers.

• Authors : Goyal V; Drugs for Neglected Diseases Initiative, New York, New York, USA.; Krantz E

Subjects: Flucytosine*; Humans ; Biological Availability

• Source: Clinical and translational science [Clin Transl Sci] 2024 Mar; Vol. 17 (3), pp. e13756.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Voriconazole plus flucytosine is not superior to amphotericin B deoxycholate plus flucytosine as an induction regimen for cryptococcal meningitis treatment.

• Authors : Zhao H; National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.; The State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

Subjects: Flucytosine*/Flucytosine*/Flucytosine*/therapeutic use ; Meningitis, Cryptococcal*/Meningitis, Cryptococcal*/Meningitis, Cryptococcal*/drug therapy ; Amphotericin B*

• Source: Mycoses [Mycoses] 2024 Jan; Vol. 67 (1), pp. e13674. Date of Electronic Publication: 2023 Nov 20.Publisher: Grosse Verlag Country of Publication: Germany NLM ID: 8805008 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Successful Treatment of Candida auris Ventriculitis With Intravenous Liposomal Amphotericin B and Oral Flucytosine: A Case Report.

• Authors : Kang, Nayoung¹ (AUTHOR); Hsu, Victor Yu-Ching² (AUTHOR); Bailey, Charles Christopher² (AUTHOR)

• Source: Open Forum Infectious Diseases. Jan2025, Vol. 12 Issue 1, p1-3. 3p.

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Identification of Low Concentrations of Flucytosine Drug Using a Surface-Enhanced Raman Scattering (SERS)-Active Filter Paper Substrate.

• Authors : Karooby, Elaheh¹ (AUTHOR); Sahbafar, Hossein^2,3 (AUTHOR); Heris, Masoud Hakimi¹ (AUTHOR)

• Source: Plasmonics. Apr2024, Vol. 19 Issue 2, p855-863. 9p.

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Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis

• Authors : Ms. Zin Win May, Principal Investigator, Clinical effectiveness and safety of Amphotericin B with Flucytosine-Fluconazole therapy for Cryptococcal meningitis in patients with HIV infection

• Source: Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis in Patients With HIV Infection

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Exponential Clonal Expansion of 5-Fluorocytosine-Resistant Candida tropicalis and New Insights into Underlying Molecular Mechanisms.

• Authors : Abou-Chakra N; Astvad KMT; Martinussen J

Subjects: Candida tropicalis*/Candida tropicalis*/Candida tropicalis*/drug effects ; Candida tropicalis*/Candida tropicalis*/Candida tropicalis*/genetics ; Candida tropicalis*/Candida tropicalis*/Candida tropicalis*/isolation & purification

• Source: Emerging infectious diseases [Emerg Infect Dis] 2025 May; Vol. 31 (5), pp. 977-985.Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155

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