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First-in-human imaging using [11C]MDTC: a radiotracer targeting the cannabinoid receptor type 2.

• Authors : Du, Yong¹ (AUTHOR); Coughlin, Jennifer M.² (AUTHOR); Brosnan, Mary Katherine¹ (AUTHOR)

• Source: European Journal of Nuclear Medicine & Molecular Imaging. Jul2023, Vol. 50 Issue 8, p2386-2393. 8p. 5 Graphs.

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Beta-Caryophyllene, a Cannabinoid Receptor Type 2 Selective Agonist, in Emotional and Cognitive Disorders.

• Authors : Ricardi, Caterina¹ (AUTHOR) ; Barachini, Serena² (AUTHOR) ; Consoli, Giorgio³ (AUTHOR)

Subjects: *CANNABINOID receptors; *COGNITION disorders; *CARYOPHYLLENE

• Source: International Journal of Molecular Sciences. Mar2024, Vol. 25 Issue 6, p3203. 19p.

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Long-Term Safety and Efficacy of Lenabasum, a Cannabinoid Receptor Type 2 Agonist, in Patients with Dermatomyositis with Refractory Skin Disease: Follow-Up Data from a 3-Year Open-Label Extension Study

• Authors : Caroline J. Stone; Geeta Ahuja; Lais Lopes Almeida Gomes

Subjects: Autoimmunity; Clinical research; Clinical trials

• Source: JID Innovations, Vol 5, Iss 1, Pp 100311- (2025)

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New Insights into Bitopic Orthosteric/Allosteric Ligands of Cannabinoid Receptor Type 2.

• Authors : Ferrisi, Rebecca¹ (AUTHOR); Polini, Beatrice² (AUTHOR); Ricardi, Caterina² (AUTHOR)

Subjects: *CANNABINOID receptors; *LIGANDS (Biochemistry); *DRUG discovery

• Source: International Journal of Molecular Sciences. Feb2023, Vol. 24 Issue 3, p2135. 14p.

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CANNABINOID RECEPTOR TYPE 2 (CB2) MODULATORS AND USES THEREOF

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Design, synthesis and biological evaluation of novel orthosteric-allosteric ligands of the cannabinoid receptor type 2 (CB2R)

• Authors : Rebecca Ferrisi; Francesca Gado; Beatrice Polini

Subjects: cannabinoid receptor type 2 (CB2R); CB2R allosteric modulators; dualsteric agents

• Source: Frontiers in Chemistry, Vol 10 (2022)

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Retraction: Improved cognition impairment by activating cannabinoid receptor type 2: Modulating CREB/BDNF expression and impeding TLR-4/NFκBp65/M1 microglia signaling pathway in D-galactose-injected ovariectomized rats.

• Authors : PLOS ONE Editors

Subjects: Medicine; Science

• Source: PLoS ONE, Vol 19, Iss 5, p e0303444 (2024)

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Synthesis, Structure–Activity Relationships, Radiofluorination, and Biological Evaluation of [18F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET

• Authors : (0000-0002-1425-0567) Teodoro, R.; (0000-0001-9743-2325) Gündel, D.; (0000-0003-3168-3062) Deuther-Conrad, W.

Subjects: cannabinoid receptor type 2; indole-2-carboxamide; binding affinity

• Source: Journal of Medicinal Chemistry 66(2023)20, 13991–14010

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Data publication: Enantioselective Synthesis, Structure Activity Relationship, Radiofluorination and Biological Evaluation of [18F]RM365, a Novel Radioligand for Imaging the Human Cannabinoid Receptor Type 2 (CB2R) in the Brain with PET

• Authors : (0000-0002-1425-0567) Teodoro, R.; (0000-0001-9743-2325) Gündel, D.; (0000-0003-3168-3062) Deuther-Conrad, W.

Subjects: cannabinoid receptor type 2; indole-2-carboxamide; binding affinity

• Source: Publication date: 2023-04-05 Open accessDOI:

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Cannabinoid receptor type 2 (CB2) modulators and uses thereof

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