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Low-Dose Anti-HIV Drug Efavirenz Mitigates Retinal Vascular Lesions in a Mouse Model of Alzheimer’s Disease

• Authors : El-Darzi, Nicole; Mast, Natalia; Buchner, David A

Subjects: Biomedical and Clinical Sciences; Ophthalmology and Optometry; Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD)

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Study of a New Anti-HIV Drug, T-20, in HIV-Infected Children

• Authors : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

• Source: A Phase I/II Study of T-20, a Fusion Inhibitor, in HIV-1 Infected ChildrenKosel B, Church J, Cunningham C, Sista P, Aweeka F. Pharmacokinetics (PK) of selected

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Using Drug Levels and Drug Resistance Testing to Select Effective Anti-HIV Drug Combinations in Patients With Drug-resistant HIV

• Source: A Phase II Study of the Predictive Value of Pharmacokinetic-Adjusted Phenotypic Susceptibility (C12h/IC50) on Antiretroviral Response to Ritonavir-Enhanced Protease Inhibitors in Subjects With Failure

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A Study to See If Taking One or Two Extra Drugs Can Lower HIV Levels in Patients Who Have Failed Their Anti-HIV Drug Treatment

• Source: A Phase II, Restrictively Randomized, Open-Label, Pilot Study of Treatment Intensification of Early Virologic Failure

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A Study to Compare the Effectiveness of Different Anti-HIV Drug Regimens in Keeping Levels of HIV in the Blood as Low as Possible

• Source: Phase II Randomized, Open-Label Study of Maintenance of HIV RNA Suppression After Switching to ddI/d4T/HU vs. ddI/d4T/EFV vs. Continuing the Pre-Entry Protease Inhibitor

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Anti-HIV Drug Regimens and Treatment-Switching Guidelines in HIV Infected Children

• Authors : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); PENTA Foundation

• Source: A Phase II/III Randomized, Open-Label Study of Combination Antiretroviral Regimens and Treatment-Switching Strategies in HIV-1-Infected Antiretroviral Naive Children

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Safety and Effectiveness of an Anti-HIV Drug Combination With and Without Hydroxyurea in Patients With Early HIV Infection

• Source: A Prospective Randomized Open-Label Clinical Trial to Evaluate the Comparative Efficacy and Safety of a Potent Antiretroviral Treatment Regimen With or Without Hydroxyurea for Subjects With Acute

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Safety and Effectiveness of Four Anti-HIV Drug Combinations in HIV-Infected Children and Teens

• Authors : Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

• Source: A Phase II Rolling Arm Master Protocol (PRAM) of Novel Antiretroviral Therapy in Stable Experienced HIV-Infected Children. PRAM-2: A Phase I/II Randomized, Multicenter

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Safety and Effectiveness of Adding Either an HIV Vaccine, Interleukin-2, or Both to a Patient's Anti-HIV Drug Combination

• Source: A Phase II, Randomized, Partially Blinded Trial of Combinations of Potent Antiretroviral Therapy, HIV-Specific Immunizations, and Cycles of Interleukin-2 to Promote

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Effect of an Enfuvirtide-based Anti-HIV Drug Regimen on Latent HIV Reservoirs in Treatment Naive Adults

• Authors : Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

• Source: A Pilot Study to Measure the Clearance of Replication-Competent HIV-1 in Resting Memory CD4+ Cells in HIV-1-Infected Subjects Who Receive

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