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  • 1-10 ل  301 نتائج ل ""Vitamin K Epoxide Reductases""
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Academic Journal

Construction of warfarin population pharmacokinetics and pharmacodynamics model in Han population based on Bayesian method.

  • Authors : Xia X; Department of Pharmacy, Fujian Maternity and Child Health Hospital College of Clinical Medicine for Obstetrics and Gynecology and Pediatrics, Fujian Medical University, #18 Daoshan Road, Fuzhou, 350001, China.; Cai X

Subjects: Anticoagulants*/Anticoagulants*/Anticoagulants*/administration & dosage ; Anticoagulants*/Anticoagulants*/Anticoagulants*/pharmacokinetics ; Cytochrome P-450 CYP2C9*/Cytochrome P-450 CYP2C9*/Cytochrome P-450 CYP2C9*/genetics

  • Source: Scientific reports [Sci Rep] 2024 Jun 27; Vol. 14 (1), pp. 14846. Date of Electronic Publication: 2024 Jun 27.Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN:

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Academic Journal

Vitamin K Epoxide Reductase Complex-Protein Disulphide Isomerase Assemblies in the Thiol-Disulphide Exchange Reactions: Portrayal of Precursor-to-Successor Complexes.

  • Authors : Stolyarchuk M; Centre Borelli, ENS Paris-Saclay, CNRS, Université Paris-Saclay, 4 Avenue des Sciences, 91190 Gif-sur-Yvette, France.; Botnari M

Subjects: Protein Disulfide-Isomerases*/Protein Disulfide-Isomerases*/Protein Disulfide-Isomerases*/metabolism ; Protein Disulfide-Isomerases*/Protein Disulfide-Isomerases*/Protein Disulfide-Isomerases*/chemistry ; Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 09; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 09.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

A physiologically-based pharmacokinetic/pharmacodynamic modeling approach for drug-drug-gene interaction evaluation of S-warfarin with fluconazole.

  • Authors : Geng K; Anhui Provincial Center for Drug Clinical Evaluation, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui, China.; Wannan Medical College, Wuhu, Anhui, China.

Subjects: Warfarin*/Warfarin*/Warfarin*/pharmacokinetics ; Warfarin*/Warfarin*/Warfarin*/pharmacology ; Warfarin*/Warfarin*/Warfarin*/administration & dosage

  • Source: CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2024 May; Vol. 13 (5), pp. 853-869. Date of Electronic Publication: 2024 Mar 15.Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN:

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Academic Journal

Is a Vitamin K Epoxide Reductase Complex Subunit 1 ( VKORC1 ) Polymorphism a Risk Factor for Nephrolithiasis in Sarcoidosis?

  • Authors : Drent M; ILD Center of Excellence, Department of Respiratory Medicine, St. Antonius Hospital, 3435 CM Nieuwegein, The Netherlands.; Department of Pharmacology and Toxicology, Faculty of Health, Medicine, and Life Science, Maastricht University, 6200 MD Maastricht, The Netherlands.

Subjects: Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/genetics ; Sarcoidosis*/Sarcoidosis*/Sarcoidosis*/genetics ; Sarcoidosis*/Sarcoidosis*/Sarcoidosis*/complications

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 18; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Synergy of Mutation-Induced Effects in Human Vitamin K Epoxide Reductase: Perspectives and Challenges for Allo-Network Modulator Design.

  • Authors : Botnari M; Centre Borelli, École Normale Supérieure (ENS) Paris-Saclay, Centre National de la Recherche Scientifique (CNRS), Université Paris-Saclay, 4 Avenue des Sciences, F-91190 Gif-sur-Yvette, France.; Tchertanov L

Subjects: Mutation, Missense* ; Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/genetics ; Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/Vitamin K Epoxide Reductases*/metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 07; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 07.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Benchmarking pharmacogenomics genotyping tools: Performance analysis on short-read sequencing samples and depth-dependent evaluation.

  • Authors : Halman A; Cancer Therapies, Stem Cell Medicine, Murdoch Children's Research Institute, Parkville, Victoria, Australia.; Victorian Clinical Genetics Services, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.

Subjects: Benchmarking* ; Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/Cytochrome P-450 CYP2D6*/genetics ; Pharmacogenetics*/Pharmacogenetics*/Pharmacogenetics*/standards

  • Source: Clinical and translational science [Clin Transl Sci] 2024 Aug; Vol. 17 (8), pp. e13911.Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Identification of the Primary Factors Determining theSpecificity of Human VKORC1 Recognition by Thioredoxin-Fold Proteins.

Subjects: Protein Domains* ; Protein Folding*; Thioredoxins/Thioredoxins/Thioredoxins/*chemistry

  • Source: International journal of molecular sciences [Int J Mol Sci] 2021 Jan 14; Vol. 22 (2). Date of Electronic Publication: 2021 Jan 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Gene variants of coagulation related proteins that interact with SARS-CoV-2.

  • Authors : Holcomb D; Center for Biologics Evaluation and Research, Office of Tissues and Advanced Therapies, Division of Plasma Protein Therapeutics, Food and Drug Administration, Silver Spring, Maryland, United States of America.; Alexaki A

Subjects: Blood Coagulation*; Blood Proteins/Blood Proteins/Blood Proteins/*genetics ; COVID-19/COVID-19/COVID-19/*metabolism

  • Source: PLoS computational biology [PLoS Comput Biol] 2021 Mar 17; Vol. 17 (3), pp. e1008805. Date of Electronic Publication: 2021 Mar 17 (Print Publication: 2021).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

New Insights on Vitamin K Metabolism in Senegalese sole ( Solea senegalensis ) Based on Ontogenetic and Tissue-Specific Vitamin K Epoxide Reductase Molecular Data.

  • Authors : Beato S; Campus de Vegazana, Universidad de León (ULE), s/n, 24071 León, Spain.; Marques C

Subjects: Organ Specificity*; Flatfishes/Flatfishes/Flatfishes/*growth & development ; Flatfishes/Flatfishes/Flatfishes/*metabolism

  • Source: International journal of molecular sciences [Int J Mol Sci] 2020 May 15; Vol. 21 (10). Date of Electronic Publication: 2020 May 15.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Editorial & Opinion

Validating two international warfarin pharmacogenetic dosing algorithms for estimating the maintenance dose for patients in Singapore.

  • Authors : Soh SPY; Department of Pharmacy, Tan Tock Seng Hospital, Singapore.; See Toh WY

Subjects: Warfarin*/Warfarin*/Warfarin*/administration & dosage ; Algorithms* ; Anticoagulants*/Anticoagulants*/Anticoagulants*/administration & dosage

  • Source: Annals of the Academy of Medicine, Singapore [Ann Acad Med Singap] 2024 Mar 27; Vol. 53 (3), pp. 208-210. Date of Electronic Publication: 2024 Mar 27.Publisher: Academy Of Medicine, Singapore Country of Publication: Singapore NLM ID: 7503289 Publication Model: Electronic Cited Medium: Internet

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  • 1-10 ل  301 نتائج ل ""Vitamin K Epoxide Reductases""