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Identification of and Structural Insights into Hit Compounds Targeting N‑Myristoyltransferase for Cryptosporidium Drug Development

• Authors : Fenwick, Michael K; Reers, Alexandra R; Liu, Yi

Subjects: Medical Microbiology; Biomedical and Clinical Sciences; Digestive Diseases

• Source: ACS Infectious Diseases. 9(10)

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Molecular Targets of the 5-Amido-Carboxamide Bumped Kinase Inhibitor BKI-1748 in Cryptosporidium parvum and HCT-8 Host Cells.

• Authors : Ajiboye, Jubilee; Uldry, Anne-Christine; Heller, Manfred

Subjects: 630 Agriculture; 610 Medicine & health

• Source: Ajiboye, Jubilee; Uldry, Anne-Christine; Heller, Manfred; Naguleswaran, Arunasalam; Fan, Erkang; Van Voorhis,

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Efficacy of the bumped kinase inhibitor BKI-1708 against the cyst-forming apicomplexan parasites Toxoplasma gondii and Neospora caninum in vitro and in experimentally infected mice

• Authors : Ferreira de Sousa, Maria Cristina; Imhof, Dennis; Hänggeli, Kai Pascal Alexander

Subjects: 636.09; Neospora; Toxoplasma

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AI is a viable alternative to high throughput screening: a 318-target study

• Authors : Wallach, Izhar; Bernard, Denzil; Nguyen, Kong ...

Subjects: Settore BIO/10; Settore BIO/19

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Clofazimine pharmacokinetics in HIV‐infected adults with diarrhea: Implications of diarrheal disease on absorption of orally administered therapeutics

• Authors : Zhang, Cindy X.; Conrad, Thomas M.; Hermann, David

Subjects: QV 38 Drug action; WC 503 Acquired immunodeficiency syndrome. HIV infections; WC 503.5 Complications

• Source: CPT: Pharmacometrics & Systems Pharmacology.

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A comparative study of eight serological methods shows that spike protein-based ELISAs are the most accurate tests for serodiagnosing SARS-CoV-2 infections in cats and dogs

• Authors : Diezma-Díaz, Carlos; Álvarez-García, Gema; Regidor-Cerrillo, Javier ...

Subjects: RBD fragment; SARS-CoV-2 virus; Cat

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Examination of ELISA against PCR for assessing treatment efficacy against Cryptosporidium in a clinical trial context.

• Authors : Nyirenda, James T.¹ (AUTHOR); Henrion, Marc Y. R.^1,2 (AUTHOR); Nyasulu, Vita¹ (AUTHOR)

Subjects: *CRYPTOSPORIDIUM; *RAPID diagnostic tests; *ESCHERICHIA coliMALAWI

• Source: PLoS ONE. 9/8/2023, Vol. 18 Issue 9, p1-12. 12p.

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Single and combination treatment of Toxoplasma gondii infections with a bumped kinase inhibitor and artemisone in vitro and with artemiside in experimentally infected mice

• Authors : Schlange, Carling; Müller, Joachim; Imhof, Dennis

Subjects: 636.09; Apicomplexa; Chemotherapy

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Editorial : Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease

• Authors : Gilbert, Ian, H; Vinayak, Sumiti; Striepen, Boris ...

Subjects: Child health; Parasitology; [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology

• Source: EISSN: 2059-7908 ; BMJ Global Health ; https://hal.inrae.fr/hal-04185758 ; BMJ Global Health, 2023, 8 (8), pp.e012540. ⟨10.1136/bmjgh-2023-012540⟩ ; https://gh.bmj.com/content/8/8/e012540.long

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Safe and effective treatments are needed for cryptosporidiosis, a truly neglected tropical disease

• Authors : Gilbert, Ian H.; Vinayak, Sumiti; Striepen, Boris

Subjects: Humans; Cryptosporidiosis/epidemiology; Neglected Diseases

• Source: Gilbert , I H , Vinayak , S , Striepen , B , Manjunatha , U H , Khalil , I A , Van Voorhis , W C &

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